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Lineage for d5to8a_ (5to8 A:)

  1. Root: SCOPe 2.06
  2. 2152203Class d: Alpha and beta proteins (a+b) [53931] (385 folds)
  3. 2195565Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
    consists of two alpha+beta domains, C-terminal domain is mostly alpha helical
  4. 2195566Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families) (S)
    shares functional and structural similarities with the ATP-grasp fold and PIPK
  5. 2195690Family d.144.1.7: Protein kinases, catalytic subunit [88854] (66 protein domains)
    members organized in the groups and subfamiles specified by the comments
  6. 2198144Protein automated matches [190091] (14 species)
    not a true protein
  7. 2198237Species Human (Homo sapiens) [TaxId:9606] [188447] (583 PDB entries)
  8. 2284218Domain d5to8a_: 5to8 A: [327519]
    automated match to d3cc6a_
    complexed with 7fm

Details for d5to8a_

PDB Entry: 5to8 (more details), 1.98 Å

PDB Description: selectivity switch between fak and pyk2: macrocyclization of fak inhibitors improves pyk2 potency
PDB Compounds: (A:) Protein-tyrosine kinase 2-beta

SCOPe Domain Sequences for d5to8a_:

Sequence, based on SEQRES records: (download)

>d5to8a_ d.144.1.7 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
iaredvvlnrilgegffgevyegvytnhkgekinvavktckkdctldnkekfmseavimk
nldhphivkligiieeeptwiimelypygelghylernknslkvltlvlyslqickamay
lesincvhrdiavrnilvaspecvklgdfglsryiededyykasvtrlpikwmspesinf
rrfttasdvwmfavcmweilsfgkqpffwlenkdvigvlekgdrlpkpdlcppvlytlmt
rcwdydpsdrprftelvcslsdvyqmekdiam

Sequence, based on observed residues (ATOM records): (download)

>d5to8a_ d.144.1.7 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
iaredvvlnrilgegffgevyegvytnhkgekinvavktckkdctnkekfmseavimknl
dhphivkligiieptwiimelypygelghylernknslkvltlvlyslqickamaylesc
vhrdiavrnilvaspecvklgdfglsrikwmspesinfrrfttasdvwmfavcmweilsf
gkqpffwlenkdvigvlekgdrlpkpdlcppvlytlmtrcwdydpsdrprftelvcslsd
vyqmekdiam

SCOPe Domain Coordinates for d5to8a_:

Click to download the PDB-style file with coordinates for d5to8a_.
(The format of our PDB-style files is described here.)

Timeline for d5to8a_:

  • d5to8a_ appears in periodic updates to SCOPe 2.06 starting on 2016-12-22