SCOPe Funding Alert: SCOPe support from the NIH ended in April 2016. John-Marc Chandonia is the primary maintainer and has continued to develop SCOPe using vacation time. Three proposals to the NIH for continued funding have been unsuccessful. If our current NIH proposal is not funded, SCOPe will shut down permanently in Summer 2017 as Dr. Chandonia will need to seek a new position.

Lineage for d5sz2a_ (5sz2 A:)

  1. Root: SCOPe 2.06
  2. 2017114Class b: All beta proteins [48724] (177 folds)
  3. 2067964Fold b.74: Carbonic anhydrase [51068] (1 superfamily)
    single sheet; 10 strands
  4. 2067965Superfamily b.74.1: Carbonic anhydrase [51069] (2 families) (S)
  5. 2067966Family b.74.1.1: Carbonic anhydrase [51070] (2 protein domains)
    automatically mapped to Pfam PF00194
  6. 2067967Protein Carbonic anhydrase [51071] (10 species)
  7. 2068005Species Human (Homo sapiens), erythrocytes, isozyme II [TaxId:9606] [51073] (631 PDB entries)
    Uniprot P00918
  8. 2284217Domain d5sz2a_: 5sz2 A: [327518]
    automated match to d4qefa_
    complexed with 72g, dms, gol, zn

Details for d5sz2a_

PDB Entry: 5sz2 (more details), 1.63 Å

PDB Description: carbonic anhydrase ii in complex with 4-(3-formylphenyl)- benzenesulfonamide
PDB Compounds: (A:) Carbonic anhydrase 2

SCOPe Domain Sequences for d5sz2a_:

Sequence; same for both SEQRES and ATOM records: (download)

>d5sz2a_ b.74.1.1 (A:) Carbonic anhydrase {Human (Homo sapiens), erythrocytes, isozyme II [TaxId: 9606]}
hwgygkhngpehwhkdfpiakgerqspvdidthtakydpslkplsvsydqatslrilnng
hafnvefddsqdkavlkggpldgtyrliqfhfhwgsldgqgsehtvdkkkyaaelhlvhw
ntkygdfgkavqqpdglavlgiflkvgsakpglqkvvdvldsiktkgksadftnfdprgl
lpesldywtypgslttppllecvtwivlkepisvsseqvlkfrklnfngegepeelmvdn
wrpaqplknrqikasfk

SCOPe Domain Coordinates for d5sz2a_:

Click to download the PDB-style file with coordinates for d5sz2a_.
(The format of our PDB-style files is described here.)

Timeline for d5sz2a_:

  • d5sz2a_ appears in periodic updates to SCOPe 2.06 starting on 2016-12-22