Lineage for d5wrnf1 (5wrn F:26-306)

  1. Root: SCOPe 2.06
  2. 2152203Class d: Alpha and beta proteins (a+b) [53931] (385 folds)
  3. 2190102Fold d.117: Thymidylate synthase/dCMP hydroxymethylase [55830] (1 superfamily)
    contains large mixed beta-sheet
  4. 2190103Superfamily d.117.1: Thymidylate synthase/dCMP hydroxymethylase [55831] (2 families) (S)
    automatically mapped to Pfam PF00303
  5. 2190104Family d.117.1.1: Thymidylate synthase/dCMP hydroxymethylase [55832] (4 protein domains)
  6. 2190142Protein Thymidylate synthase [55833] (7 species)
  7. 2190283Species Human (Homo sapiens) [TaxId:9606] [55840] (26 PDB entries)
  8. 2283948Domain d5wrnf1: 5wrn F:26-306 [327249]
    Other proteins in same PDB: d5wrna2, d5wrnb2, d5wrnc2, d5wrnd2, d5wrne2, d5wrnf2
    automated match to d1hvya_
    complexed with dc

Details for d5wrnf1

PDB Entry: 5wrn (more details), 2.39 Å

PDB Description: human thymidylate synthase complexed with dcmp
PDB Compounds: (F:) Thymidylate synthase

SCOPe Domain Sequences for d5wrnf1:

Sequence, based on SEQRES records: (download)

>d5wrnf1 d.117.1.1 (F:26-306) Thymidylate synthase {Human (Homo sapiens) [TaxId: 9606]}
pphgelqylgqiqhilrcgvrkddrtgtgtlsvfgmqaryslrdefpllttkrvfwkgvl
eellwfikgstnakelsskgvkiwdangsrdfldslgfstreegdlgpvygfqwrhfgae
yrdmesdysgqgvdqlqrvidtiktnpddrriimcawnprdlplmalppchalcqfyvvn
selscqlyqrsgdmglgvpfniasyalltymiahitglkpgdfihtlgdahiylnhiepl
kiqlqreprpfpklrilrkvekiddfkaedfqiegynphpt

Sequence, based on observed residues (ATOM records): (download)

>d5wrnf1 d.117.1.1 (F:26-306) Thymidylate synthase {Human (Homo sapiens) [TaxId: 9606]}
pphgelqylgqiqhilrcgvrkdgtlsvfgmqaryslrdefpllttkrvfwkgvleellw
fikgstnakelsskgvkiwdangsrdfldslgfstreegdlgpvygfqwrhfgaeyrdme
sdysgqgvdqlqrvidtiktnpddrriimcawnprdlplmalppchalcqfyvvnselsc
qlyqrsgdmglgvpfniasyalltymiahitglkpgdfihtlgdahiylnhieplkiqlq
reprpfpklrilrkvekiddfkaedfqiegynphpt

SCOPe Domain Coordinates for d5wrnf1:

Click to download the PDB-style file with coordinates for d5wrnf1.
(The format of our PDB-style files is described here.)

Timeline for d5wrnf1:

  • d5wrnf1 appears in periodic updates to SCOPe 2.06 starting on 2016-12-15