SCOPe Funding Alert: SCOPe support from the NIH ended in April 2016. John-Marc Chandonia is the primary maintainer and has continued to develop SCOPe using vacation time. Three proposals to the NIH for continued funding have been unsuccessful. If our current NIH proposal is not funded, SCOPe will shut down permanently in Summer 2017 as Dr. Chandonia will need to seek a new position.

Lineage for d5gpia_ (5gpi A:)

  1. Root: SCOPe 2.06
  2. 2229111Class g: Small proteins [56992] (94 folds)
  3. 2237459Fold g.96: Flavivirus non-structural protein NS2B-like [310561] (1 superfamily)
  4. 2237460Superfamily g.96.1: Flavivirus non-structural protein NS2B-like [310588] (2 families) (S)
    Pfam PF01002; see PubMed 16532006 for discussion of NS2B-NS3pro complex
  5. 2281084Family g.96.1.0: automated matches [324385] (1 protein)
    not a true family
  6. 2281085Protein automated matches [324386] (2 species)
    not a true protein
  7. 2283836Species Zika virus [TaxId:64320] [327137] (2 PDB entries)
  8. 2283852Domain d5gpia_: 5gpi A: [327153]
    Other proteins in same PDB: d5gpib_, d5gpid_, d5gpif_, d5gpih_
    automated match to d2ggva_

Details for d5gpia_

PDB Entry: 5gpi (more details), 1.58 Å

PDB Description: crystal structures of unlinked ns2b-ns3 protease from zika virus and its complex with a reverse peptide inhibitor
PDB Compounds: (A:) NS2B cofactor

SCOPe Domain Sequences for d5gpia_:

Sequence; same for both SEQRES and ATOM records: (download)

>d5gpia_ g.96.1.0 (A:) automated matches {Zika virus [TaxId: 64320]}
dmyieragditwekdaevtgnsprldvaldesgdfslv

SCOPe Domain Coordinates for d5gpia_:

Click to download the PDB-style file with coordinates for d5gpia_.
(The format of our PDB-style files is described here.)

Timeline for d5gpia_:

  • d5gpia_ appears in periodic updates to SCOPe 2.06 starting on 2016-12-15