SCOPe Funding Alert: SCOPe support from the NIH ended in April 2016. John-Marc Chandonia is the primary maintainer and has continued to develop SCOPe using vacation time. Three proposals to the NIH for continued funding have been unsuccessful. If our current NIH proposal is not funded, SCOPe will shut down permanently in Summer 2017 as Dr. Chandonia will need to seek a new position.

Lineage for d5gp1b_ (5gp1 B:)

  1. Root: SCOPe 2.06
  2. 2078559Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2129295Fold c.66: S-adenosyl-L-methionine-dependent methyltransferases [53334] (1 superfamily)
    core: 3 layers, a/b/a; mixed beta-sheet of 7 strands, order 3214576; strand 7 is antiparallel to the rest
  4. 2129296Superfamily c.66.1: S-adenosyl-L-methionine-dependent methyltransferases [53335] (60 families) (S)
  5. 2130608Family c.66.1.0: automated matches [191451] (1 protein)
    not a true family
  6. 2130609Protein automated matches [190689] (60 species)
    not a true protein
  7. 2283621Species Zika virus [TaxId:64320] [326922] (1 PDB entry)
  8. 2283626Domain d5gp1b_: 5gp1 B: [326927]
    automated match to d2oxta_
    complexed with gta, ni, sah, so4

Details for d5gp1b_

PDB Entry: 5gp1 (more details), 2.44 Å

PDB Description: crystal structure of zikv ns5 methyltransferase in complex with gtp and sah
PDB Compounds: (B:) RNA-directed RNA polymerase NS5

SCOPe Domain Sequences for d5gp1b_:

Sequence; same for both SEQRES and ATOM records: (download)

>d5gp1b_ c.66.1.0 (B:) automated matches {Zika virus [TaxId: 64320]}
etlgekwkarlnqmsalefysykksgitevcreearralkdgvatgghavsrgsaklrwl
vergylqpygkvidlgcgrggwsyyaatirkvqevkgytkggpgheepmlvqsygwnivr
lksgvdvfhmaaepcdtllcdigesssspeveeartlrvlsmvgdwlekrpgafcikvlc
pytstmmetlerlqrryggglvrvplsrnsthemywvsgaksntiksvsttsqlllgrmd
gprrpvkyeedvnlgsgtra

SCOPe Domain Coordinates for d5gp1b_:

Click to download the PDB-style file with coordinates for d5gp1b_.
(The format of our PDB-style files is described here.)

Timeline for d5gp1b_:

  • d5gp1b_ appears in periodic updates to SCOPe 2.06 starting on 2016-12-08