SCOP 1.73: Domain d2hnpa_: 2hnp A:

Lineage for d2hnpa_ (2hnp A:)

1. Root: SCOP 1.73

2. Class c: Alpha and beta proteins (a/b) [51349] (141 folds)

3. Fold c.45: (Phosphotyrosine protein) phosphatases II [52798] (1 superfamily)
   core: 3 layers, a/b/a; parallel beta-sheet of 4 strands, order 1423

4. Superfamily c.45.1: (Phosphotyrosine protein) phosphatases II [52799] (5 families)
   share with the family I the common active site structure with a circularly permuted topology

5. Family c.45.1.2: Higher-molecular-weight phosphotyrosine protein phosphatases [52805] (6 proteins)
   has an extension to the beta-sheet of 3 antiparallel strands before strand 4

6. Protein Tyrosine phosphatase [52806] (7 species)

7. Species Human (Homo sapiens), 1B [TaxId:9606] [52807] (91 PDB entries)

8. Domain d2hnpa_: 2hnp A: [32678]

Details for d2hnpa_

PDB Entry: 2hnp, 2.8 Å

PDB Description: crystal structure of human protein tyrosine phosphatase 1b

PDB Compounds: (A:) protein-tyrosine phosphatase-1b

SCOP Domain Sequences for d2hnpa_:

Sequence; same for both SEQRES and ATOM records:

>d2hnpa_ c.45.1.2 (A:) Tyrosine phosphatase {Human (Homo sapiens), 1B [TaxId: 9606]}
kefeqidksgswaaiyqdirheasdfpcrvaklpknknrnryrdvspfdhsriklhqedn
dyinaslikmeeaqrsyiltqgplpntcghfwemvweqksrgvvmlnrvmekgslkcaqy
wpqkeekemifedtnlkltlisediksyytvrqlelenlttqetreilhfhyttwpdfgv
pespasflnflfkvresgslspehgpvvvhcsagigrsgtfcladtclllmdkrkdpssv
dikkvllemrkfrmgliqtadqlrfsylaviegakfim

Timeline for d2hnpa_:

• d2hnpa_ first appeared (with stable ids) in SCOP 1.55, called d2hnp__
  
• d2hnpa_ was called d2hnp__ in SCOP 1.71
  
• d2hnpa_ appears in SCOP 1.75
  
• d2hnpa_ appears in the current release, SCOPe 2.08