SCOPe Funding Alert: SCOPe support from the NIH ended in April 2016. John-Marc Chandonia is the primary maintainer and has continued to develop SCOPe using vacation time. Three proposals to the NIH for continued funding have been unsuccessful. If our current NIH proposal is not funded, SCOPe will shut down permanently in Summer 2017 as Dr. Chandonia will need to seek a new position.

Lineage for d5t6db_ (5t6d B:)

  1. Root: SCOPe 2.06
  2. 2017114Class b: All beta proteins [48724] (177 folds)
  3. 2055629Fold b.47: Trypsin-like serine proteases [50493] (1 superfamily)
    barrel, closed; n=6, S=8; greek-key
    duplication: consists of two domains of the same fold
  4. 2055630Superfamily b.47.1: Trypsin-like serine proteases [50494] (5 families) (S)
  5. 2057856Family b.47.1.4: Viral cysteine protease of trypsin fold [50603] (5 protein domains)
  6. 2058054Protein automated matches [190384] (19 species)
    not a true protein
  7. 2270301Species Norwalk virus [TaxId:524364] [313606] (10 PDB entries)
  8. 2283249Domain d5t6db_: 5t6d B: [326550]
    Other proteins in same PDB: d5t6da2
    automated match to d2fyqa_
    complexed with n38

Details for d5t6db_

PDB Entry: 5t6d (more details), 2.1 Å

PDB Description: 2.10 a resolution structure of norovirus 3cl protease in complex with the dipeptidyl inhibitor 7l (hexagonal form)
PDB Compounds: (B:) Genome polyprotein

SCOPe Domain Sequences for d5t6db_:

Sequence, based on SEQRES records: (download)

>d5t6db_ b.47.1.4 (B:) automated matches {Norwalk virus [TaxId: 524364]}
tlwsrvtkfgsgwgfwvsptvfittthvvptgvkeffgeplssiaihqageftqfrfskk
mrpdltgmvleegcpegtvcsvlikrdsgellplavrmgaiasmriqgrlvhgqsgmllt
ganakgmdlgtipgdcgapyvhkrgndwvvcgvhaaatksgntvvcavq

Sequence, based on observed residues (ATOM records): (download)

>d5t6db_ b.47.1.4 (B:) automated matches {Norwalk virus [TaxId: 524364]}
tlwsrvtkfgsgwgfwvsptvfittthvvptgvkeffgeplssiaihqageftqfrfskk
mrpdltgmvleegcpegtvcsvlikrdsgellplavrmgaiasmriqgrlvhgqsgmllt
lgtipgdcgapyvhkrgndwvvcgvhaaatksgntvvcavq

SCOPe Domain Coordinates for d5t6db_:

Click to download the PDB-style file with coordinates for d5t6db_.
(The format of our PDB-style files is described here.)

Timeline for d5t6db_:

  • d5t6db_ appears in periodic updates to SCOPe 2.06 starting on 2016-11-24