Lineage for d5hora_ (5hor A:)

  1. Root: SCOPe 2.06
  2. 2152203Class d: Alpha and beta proteins (a+b) [53931] (385 folds)
  3. 2195565Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
    consists of two alpha+beta domains, C-terminal domain is mostly alpha helical
  4. 2195566Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families) (S)
    shares functional and structural similarities with the ATP-grasp fold and PIPK
  5. 2195690Family d.144.1.7: Protein kinases, catalytic subunit [88854] (66 protein domains)
    members organized in the groups and subfamiles specified by the comments
  6. 2197126Protein Hepatocyte growth factor receptor, c-MET [103300] (1 species)
    PTK group; HGFR subfamily; membrane spanning protein tyrosine kinase
  7. 2197127Species Human (Homo sapiens) [TaxId:9606] [103301] (52 PDB entries)
  8. 2283224Domain d5hora_: 5hor A: [326525]
    automated match to d1r0pa_
    complexed with 63k

Details for d5hora_

PDB Entry: 5hor (more details), 2.2 Å

PDB Description: crystal structure of c-met-m1250t in complex with sar125844.
PDB Compounds: (A:) Hepatocyte growth factor receptor

SCOPe Domain Sequences for d5hora_:

Sequence, based on SEQRES records: (download)

>d5hora_ d.144.1.7 (A:) Hepatocyte growth factor receptor, c-MET {Human (Homo sapiens) [TaxId: 9606]}
qavqhvvigpsslivhfnevigrghfgcvyhgtlldndgkkihcavkslnritdigevsq
fltegiimkdfshpnvlsllgiclrsegsplvvlpymkhgdlrnfirnethnptvkdlig
fglqvakgmkflaskkfvhrdlaarncmldekftvkvadfglardmydkefdsvhnktga
klpvkwtaleslqtqkfttksdvwsfgvllwelmtrgappypdvntfditvyllqgrrll
qpeycpdplyevmlkcwhpkaemrpsfselvsrisaifstfigehyvhvnaty

Sequence, based on observed residues (ATOM records): (download)

>d5hora_ d.144.1.7 (A:) Hepatocyte growth factor receptor, c-MET {Human (Homo sapiens) [TaxId: 9606]}
qavqhvvigpgcvyhgtlkihcavksvsqfltegiimkdfshpnvlsllgiclrsegspl
vvlpymkhgdlrnfirnethnptvkdligfglqvakgmkflaskkfvhrdlaarncmlde
kftvkvadfglardmlpvkwtaleslqtqkfttksdvwsfgvllwelmtrgappypdvnt
fditvyllqgrrllqpeycpdplyevmlkcwhpkaemrpsfselvsrisaifstfigehy
vhvnaty

SCOPe Domain Coordinates for d5hora_:

Click to download the PDB-style file with coordinates for d5hora_.
(The format of our PDB-style files is described here.)

Timeline for d5hora_:

  • d5hora_ appears in periodic updates to SCOPe 2.06 starting on 2016-11-24