SCOPe Funding Alert: SCOPe support from the NIH ended in April 2016. John-Marc Chandonia is the primary maintainer and has continued to develop SCOPe using vacation time. Three proposals to the NIH for continued funding have been unsuccessful. If our current NIH proposal is not funded, SCOPe will shut down permanently in Summer 2017 as Dr. Chandonia will need to seek a new position.

Lineage for d5ko1a_ (5ko1 A:)

  1. Root: SCOPe 2.06
  2. 2152203Class d: Alpha and beta proteins (a+b) [53931] (385 folds)
  3. 2195565Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
    consists of two alpha+beta domains, C-terminal domain is mostly alpha helical
  4. 2195566Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families) (S)
    shares functional and structural similarities with the ATP-grasp fold and PIPK
  5. 2199100Family d.144.1.0: automated matches [191359] (1 protein)
    not a true family
  6. 2199101Protein automated matches [190417] (25 species)
    not a true protein
  7. 2199241Species Human (Homo sapiens) [TaxId:9606] [187294] (808 PDB entries)
  8. 2283002Domain d5ko1a_: 5ko1 A: [326303]
    automated match to d4m67a_
    complexed with 6uy

Details for d5ko1a_

PDB Entry: 5ko1 (more details), 2.16 Å

PDB Description: pseudokinase domain of mlkl bound to compound 4.
PDB Compounds: (A:) mixed lineage kinase domain-like protein

SCOPe Domain Sequences for d5ko1a_:

Sequence, based on SEQRES records: (download)

>d5ko1a_ d.144.1.0 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
qikeikkeqlsgspwillrenevstlykgeyhrapvaikvfkklqagsiaivrqtfnkei
ktmkkfespnilrifgicidetvtppqfsivmeycelgtlrelldrekdltlgkrmvlvl
gaarglyrlhhseapelhgkirssnflvtqgyqvklagfelrktqtsmslgttraatdrv
kstaylspqeledvfyqydvkseiysfgivlweiatgdipfqgcnsekirklvavkrqqe
plgedcpselreiidecrahdpsvrpsvdeilkklstfs

Sequence, based on observed residues (ATOM records): (download)

>d5ko1a_ d.144.1.0 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
qikeikkeqlsgspwillrenevstlykgeyhrapvaikvfkklqagsiaivrqtfnkei
ktmkkfespnilrifgicidetvtppqfsivmeycelgtlrelldrekdltlgkrmvlvl
gaarglyrlhhseapelhgkirssnflvtqgyqvklagfelrkdrvkstaylspqeledv
fyqydvkseiysfgivlweiatgdipfqgcnsekirklvavkrqqeplgedcpselreii
decrahdpsvrpsvdeilkklstfs

SCOPe Domain Coordinates for d5ko1a_:

Click to download the PDB-style file with coordinates for d5ko1a_.
(The format of our PDB-style files is described here.)

Timeline for d5ko1a_:

  • d5ko1a_ appears in periodic updates to SCOPe 2.06 starting on 2016-11-17