Lineage for d5l6ay_ (5l6a Y:)

  1. Root: SCOPe 2.07
  2. 2494617Class d: Alpha and beta proteins (a+b) [53931] (388 folds)
  3. 2548740Fold d.153: Ntn hydrolase-like [56234] (2 superfamilies)
    4 layers: alpha/beta/beta/alpha; has an unusual sheet-to-sheet packing
  4. 2548741Superfamily d.153.1: N-terminal nucleophile aminohydrolases (Ntn hydrolases) [56235] (8 families) (S)
    N-terminal residue provides two catalytic groups, nucleophile and proton donor
  5. 2548925Family d.153.1.4: Proteasome subunits [56251] (4 proteins)
  6. 2549037Protein Proteasome alpha subunit (non-catalytic) [56255] (9 species)
    contains an extension to the common fold at the N-terminus
  7. 2549053Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [56257] (235 PDB entries)
    The structure of yeast proteasome complexed with the proteasome activator pa26 is available from PDB (1fnt). The 1FNT entry designates protein chains by both upper case and lower case letters creating problems with its processing and presentation in SCOP; the proteasome activator pa26 structure is classified elsewhere in SCOP (a.24.8)
  8. 2550141Domain d5l6ay_: 5l6a Y: [326056]
    Other proteins in same PDB: d5l6aa_, d5l6ab_, d5l6ac_, d5l6ad_, d5l6ae_, d5l6af_, d5l6ah_, d5l6ai_, d5l6aj_, d5l6am_, d5l6an_, d5l6ao_, d5l6ap_, d5l6aq_, d5l6ar_, d5l6as_, d5l6at_, d5l6av_, d5l6aw_, d5l6ax_
    automated match to d5cgfk_
    complexed with 79l, cl, mes, mg

Details for d5l6ay_

PDB Entry: 5l6a (more details), 2.8 Å

PDB Description: yeast 20s proteasome with mouse beta5i (1-138) and mouse beta6 (97- 111; 118-133) in complex with epoxyketone inhibitor 17
PDB Compounds: (Y:) Proteasome subunit beta type-8,Proteasome subunit beta type-5

SCOPe Domain Sequences for d5l6ay_:

Sequence; same for both SEQRES and ATOM records: (download)

>d5l6ay_ d.153.1.4 (Y:) Proteasome alpha subunit (non-catalytic) {Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932]}

SCOPe Domain Coordinates for d5l6ay_:

Click to download the PDB-style file with coordinates for d5l6ay_.
(The format of our PDB-style files is described here.)

Timeline for d5l6ay_: