Lineage for d5l63w_ (5l63 W:)

  1. Root: SCOPe 2.06
  2. 2152203Class d: Alpha and beta proteins (a+b) [53931] (385 folds)
  3. 2201124Fold d.153: Ntn hydrolase-like [56234] (2 superfamilies)
    4 layers: alpha/beta/beta/alpha; has an unusual sheet-to-sheet packing
  4. 2201125Superfamily d.153.1: N-terminal nucleophile aminohydrolases (Ntn hydrolases) [56235] (8 families) (S)
    N-terminal residue provides two catalytic groups, nucleophile and proton donor
  5. 2201309Family d.153.1.4: Proteasome subunits [56251] (4 protein domains)
  6. 2202517Protein Proteasome beta subunit (catalytic) [56252] (6 species)
  7. 2202526Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [56254] (174 PDB entries)
    The structure of yeast proteasome complexed with the proteasome activator pa26 is available from PDB (1fnt). The 1FNT entry designates protein chains by both upper case and lower case letters creating problems with its processing and presentation in SCOP; the proteasome activator pa26 structure is classified elsewhere in SCOP (a.24.8)
  8. 2282447Domain d5l63w_: 5l63 W: [325748]
    Other proteins in same PDB: d5l63b_, d5l63c_, d5l63d_, d5l63e_, d5l63f_, d5l63g_, d5l63h_, d5l63k_, d5l63l_, d5l63m_, d5l63p_, d5l63q_, d5l63r_, d5l63s_, d5l63t_, d5l63u_, d5l63v_, d5l63y_, d5l63z_
    automated match to d1g0ui_
    complexed with 04c, cl, mes, mg

Details for d5l63w_

PDB Entry: 5l63 (more details), 2.7 Å

PDB Description: yeast 20s proteasome with human beta5c (1-138) and human beta6 (97- 111; 118-133) in complex with epoxyketone inhibitor 17
PDB Compounds: (W:) Proteasome subunit beta type-3

SCOPe Domain Sequences for d5l63w_:

Sequence; same for both SEQRES and ATOM records: (download)

>d5l63w_ d.153.1.4 (W:) Proteasome beta subunit (catalytic) {Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932]}
sdpssinggivvamtgkdcvaiacdlrlgsqslgvsnkfekifhyghvflgitglatdvt
tlnemfryktnlyklkeeraiepetftqlvssslyerrfgpyfvgpvvaginsksgkpfi
agfdligcideakdfivsgtasdqlfgmceslyepnlepedlfetisqallnaadrdals
gwgavvyiikkdevvkrylkmrqd

SCOPe Domain Coordinates for d5l63w_:

Click to download the PDB-style file with coordinates for d5l63w_.
(The format of our PDB-style files is described here.)

Timeline for d5l63w_:

  • d5l63w_ appears in periodic updates to SCOPe 2.06 starting on 2016-11-12