Lineage for d5l5is_ (5l5i S:)

  1. Root: SCOPe 2.06
  2. 2152203Class d: Alpha and beta proteins (a+b) [53931] (385 folds)
  3. 2201124Fold d.153: Ntn hydrolase-like [56234] (2 superfamilies)
    4 layers: alpha/beta/beta/alpha; has an unusual sheet-to-sheet packing
  4. 2201125Superfamily d.153.1: N-terminal nucleophile aminohydrolases (Ntn hydrolases) [56235] (8 families) (S)
    N-terminal residue provides two catalytic groups, nucleophile and proton donor
  5. 2201309Family d.153.1.4: Proteasome subunits [56251] (4 protein domains)
  6. 2203920Protein automated matches [190144] (11 species)
    not a true protein
  7. 2204191Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:559292] [189752] (157 PDB entries)
  8. 2282219Domain d5l5is_: 5l5i S: [325520]
    Other proteins in same PDB: d5l5ia_, d5l5ib_, d5l5ic_, d5l5id_, d5l5if_, d5l5ig_, d5l5ii_, d5l5ij_, d5l5ik_, d5l5il_, d5l5io_, d5l5ip_, d5l5iq_, d5l5ir_, d5l5it_, d5l5iu_, d5l5iw_, d5l5ix_, d5l5iy_, d5l5iz_
    automated match to d4g4se_
    complexed with 38x, cl, mes, mg

Details for d5l5is_

PDB Entry: 5l5i (more details), 2.9 Å

PDB Description: yeast 20s proteasome with human beta5i (1-138) and human beta6 (97- 111; 118-133) in complex with epoxyketone inhibitor 9
PDB Compounds: (S:) Proteasome subunit alpha type-6

SCOPe Domain Sequences for d5l5is_:

Sequence; same for both SEQRES and ATOM records: (download)

>d5l5is_ d.153.1.4 (S:) automated matches {Baker's yeast (Saccharomyces cerevisiae) [TaxId: 559292]}
nnydgdtvtfsptgrlfqveyaleaikqgsvtvglrsnthavlvalkrnadelssyqkki
ikcdehmglslaglapdarvlsnylrqqcnysslvfnrklaveraghllcdkaqkntqsy
ggrpygvglliigydksgahllefqpsgnvtelygtaigarsqgaktylertldtfikid
gnpdelikagveaisqslrdesltvdnlsiaivgkdtpftiydgeavakyi

SCOPe Domain Coordinates for d5l5is_:

Click to download the PDB-style file with coordinates for d5l5is_.
(The format of our PDB-style files is described here.)

Timeline for d5l5is_:

  • d5l5is_ appears in periodic updates to SCOPe 2.06 starting on 2016-11-11