SCOPe 2.08: Domain d5ktwa1: 5ktw A:1085-1196

Lineage for d5ktwa1 (5ktw A:1085-1196)

1. Root: SCOPe 2.08

2. Class a: All alpha proteins [46456] (290 folds)

3. Fold a.29: Bromodomain-like [47363] (15 superfamilies)
   4 helices; bundle; minor mirror variant of up-and-down topology

4. Superfamily a.29.2: Bromodomain [47370] (2 families)

5. Family a.29.2.1: Bromodomain [47371] (6 proteins)

6. Protein CREB-binding protein, CBP [74712] (2 species)

7. Species Human (Homo sapiens) [TaxId:9606] [74713] (59 PDB entries)

8. Domain d5ktwa1: 5ktw A:1085-1196 [324713]
   Other proteins in same PDB: d5ktwa2, d5ktwb2, d5ktwc2
   automated match to d4nyxa_
   complexed with 6xg, edo

Details for d5ktwa1

PDB Entry: 5ktw, 1.09 Å

PDB Description: crebbp bromodomain in complex with cpd 44 (3-((5-acetyl-1- (cyclopropylmethyl)-4,5,6,7-tetrahydro-1h-pyrazolo[4,3-c]pyridin-3- yl)amino)-n-isopropylbenzamide)

PDB Compounds: (A:) creb-binding protein

SCOPe Domain Sequences for d5ktwa1:

Sequence; same for both SEQRES and ATOM records:

>d5ktwa1 a.29.2.1 (A:1085-1196) CREB-binding protein, CBP {Human (Homo sapiens) [TaxId: 9606]}
fkpeelrqalmptlealyrqdpeslpfrqpvdpqllgipdyfdivknpmdlstikrkldt
gqyqepwqyvddvwlmfnnawlynrktsrvykfcsklaevfeqeidpvmqal

Timeline for d5ktwa1:

• d5ktwa1 first appeared in SCOPe 2.06
  
• d5ktwa1 appears in SCOPe 2.07