SCOP 1.73: Domain d1heia2: 1hei A:326-629

Lineage for d1heia2 (1hei A:326-629)

1. Root: SCOP 1.73

2. Class c: Alpha and beta proteins (a/b) [51349] (141 folds)

3. Fold c.37: P-loop containing nucleoside triphosphate hydrolases [52539] (1 superfamily)
   3 layers: a/b/a, parallel or mixed beta-sheets of variable sizes

4. Superfamily c.37.1: P-loop containing nucleoside triphosphate hydrolases [52540] (24 families)
   division into families based on beta-sheet topologies

5. Family c.37.1.14: RNA helicase [52724] (3 proteins)
   duplication: consists of two similar domains, one binds NTP and the other binds RNA; also contains an all-alpha subdomain in the C-terminal extension

6. Protein HCV helicase domain [52725] (1 species)

7. Species Human hepatitis C virus (HCV), different isolates [TaxId:11103] [52726] (6 PDB entries)

8. Domain d1heia2: 1hei A:326-629 [32464]

Details for d1heia2

PDB Entry: 1hei, 2.1 Å

PDB Description: structure of the hepatitis c virus rna helicase domain

PDB Compounds: (A:) hcv helicase

SCOP Domain Sequences for d1heia2:

Sequence; same for both SEQRES and ATOM records:

>d1heia2 c.37.1.14 (A:326-629) HCV helicase domain {Human hepatitis C virus (HCV), different isolates [TaxId: 11103]}
pgsvtvshpnieevalsttgeipfygkaiplevikggrhlifchskkkcdelaaklvalg
inavayyrgldvsviptngdvvvvstdalmtgftgdfdsvidcntcvtqtvdfsldptft
ietttlpqdavsrtqrrgrtgrgkpgiyrfvapgerpsgmfdssvlcecydagcawyelm
paettvrlraymntpglpvcqdhlefwegvftglthidahflsqtkqsgenfpylvayqa
tvcaraqapppswdqmwkclirlkptlhgptpllyrlgavqnevtlthpitkyimtcmsa
dlev

Timeline for d1heia2:

• d1heia2 first appeared (with stable ids) in SCOP 1.55
  
• d1heia2 appears in SCOP 1.71
  
• d1heia2 appears in SCOP 1.75
  
• d1heia2 appears in the current release, SCOPe 2.08