SCOPe 2.08: Domain d5kupa1: 5kup A:394-657

Lineage for d5kupa1 (5kup A:394-657)

1. Root: SCOPe 2.08

2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.7: Protein kinases, catalytic subunit [88854] (66 proteins)
   members organized in the groups and subfamiles specified by the comments

6. Protein automated matches [190091] (20 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [188447] (850 PDB entries)

8. Domain d5kupa1: 5kup A:394-657 [322720]
   Other proteins in same PDB: d5kupa2
   automated match to d4z3va_
   complexed with 6xl, gol, pg0, so4

Details for d5kupa1

PDB Entry: 5kup, 1.39 Å

PDB Description: bruton's tyrosine kinase (btk) with pyridazinone compound 9

PDB Compounds: (A:) Tyrosine-protein kinase BTK

SCOPe Domain Sequences for d5kupa1:

Sequence; same for both SEQRES and ATOM records:

>d5kupa1 d.144.1.7 (A:394-657) automated matches {Human (Homo sapiens) [TaxId: 9606]}
sweidpkdltflkelgtgqfgvvkygkwrgqydvaikmikegsmsedefieeakvmmnls
heklvqlygvctkqrpifiiteymangcllnylremrhrfqtqqllemckdvceameyle
skqflhrdlaarnclvndqgvvkvsdfglsryvlddeytssvgskfpvrwsppevlmysk
fssksdiwafgvlmweiyslgkmpyerftnsetaehiaqglrlyrphlasekvytimysc
whekaderptfkillsnildvmde

Timeline for d5kupa1:

• d5kupa1 first appeared in SCOPe 2.06
  
• d5kupa1 appears in SCOPe 2.07