Lineage for d5p8wc_ (5p8w C:)

  1. Root: SCOPe 2.07
  2. 2413226Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2468838Fold c.66: S-adenosyl-L-methionine-dependent methyltransferases [53334] (1 superfamily)
    core: 3 layers, a/b/a; mixed beta-sheet of 7 strands, order 3214576; strand 7 is antiparallel to the rest
  4. 2468839Superfamily c.66.1: S-adenosyl-L-methionine-dependent methyltransferases [53335] (60 families) (S)
  5. 2468840Family c.66.1.1: COMT-like [53336] (4 proteins)
  6. 2468851Protein Catechol O-methyltransferase, COMT [53337] (2 species)
  7. 2468864Species Norway rat (Rattus norvegicus) [TaxId:10116] [53338] (86 PDB entries)
  8. 2468955Domain d5p8wc_: 5p8w C: [322309]
    automated match to d4pyna_
    complexed with dtt, fmt, na, o01

Details for d5p8wc_

PDB Entry: 5p8w (more details), 2.03 Å

PDB Description: crystal structure of comt in complex with [5-(2,4-dimethyl-1,3- thiazol-5-yl)-1h-pyrazol-3-yl]methanamine
PDB Compounds: (C:) Catechol O-methyltransferase

SCOPe Domain Sequences for d5p8wc_:

Sequence, based on SEQRES records: (download)

>d5p8wc_ c.66.1.1 (C:) Catechol O-methyltransferase, COMT {Norway rat (Rattus norvegicus) [TaxId: 10116]}
dtkeqrilryvqqnakpgdpqsvleaidtyctqkewamnvgdakgqimdavireyspslv
lelgaycgysavrmarllqpgarlltmeinpdcaaitqqmlnfaglqdkvtilngasqdl
ipqlkkkydvdtldmvfldhwkdrylpdtlllekcgllrkgtvlladnvivpgtpdflay
vrgsssfecthyssyleymkvvdglekaiyqgps

Sequence, based on observed residues (ATOM records): (download)

>d5p8wc_ c.66.1.1 (C:) Catechol O-methyltransferase, COMT {Norway rat (Rattus norvegicus) [TaxId: 10116]}
dtkeqrilryvqqnakpgdpqsvleaidtyctqkamnvgdakgqimdavireyspslvle
lgaycgysavrmarllqpgarlltmeinpdcaaitqqmlnfaglqdkvtilngasqdlip
qlkkkydvdtldmvfldhwkdrylpdtlllekcgllrkgtvlladnvivpgtpdflayvr
gsssfecthyssyleymkvvdglekaiyqgps

SCOPe Domain Coordinates for d5p8wc_:

Click to download the PDB-style file with coordinates for d5p8wc_.
(The format of our PDB-style files is described here.)

Timeline for d5p8wc_: