Lineage for d5lr6a_ (5lr6 A:)

  1. Root: SCOPe 2.07
  2. 2413226Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2468838Fold c.66: S-adenosyl-L-methionine-dependent methyltransferases [53334] (1 superfamily)
    core: 3 layers, a/b/a; mixed beta-sheet of 7 strands, order 3214576; strand 7 is antiparallel to the rest
  4. 2468839Superfamily c.66.1: S-adenosyl-L-methionine-dependent methyltransferases [53335] (60 families) (S)
  5. 2468840Family c.66.1.1: COMT-like [53336] (4 proteins)
  6. 2468851Protein Catechol O-methyltransferase, COMT [53337] (2 species)
  7. 2468864Species Norway rat (Rattus norvegicus) [TaxId:10116] [53338] (86 PDB entries)
  8. 2468964Domain d5lr6a_: 5lr6 A: [322087]
    automated match to d4pyna_
    complexed with 731, cl, nhe

Details for d5lr6a_

PDB Entry: 5lr6 (more details), 2.3 Å

PDB Description: crystal structure of comt in complex with [3-(2,4-dimethyl-1,3- thiazol-5-yl)-1h-pyrazol-5-yl]-(4-phenylpiperazin-1-yl)methanone
PDB Compounds: (A:) Catechol O-methyltransferase

SCOPe Domain Sequences for d5lr6a_:

Sequence, based on SEQRES records: (download)

>d5lr6a_ c.66.1.1 (A:) Catechol O-methyltransferase, COMT {Norway rat (Rattus norvegicus) [TaxId: 10116]}
gdtkeqrilryvqqnakpgdpqsvleaidtyctqkewamnvgdakgqimdavireyspsl
vlelgaycgysavrmarllqpgarlltmeinpdcaaitqqmlnfaglqdkvtilngasqd
lipqlkkkydvdtldmvfldhwkdrylpdtlllekcgllrkgtvlladnvivpgtpdfla
yvrgsssfecthyssyleymkvvdglekaiyqgps

Sequence, based on observed residues (ATOM records): (download)

>d5lr6a_ c.66.1.1 (A:) Catechol O-methyltransferase, COMT {Norway rat (Rattus norvegicus) [TaxId: 10116]}
gdtkeqrilryvqqnakpgdpqsvleaidtyctqkewamvgdakgqimdavireyspslv
lelgaycgysavrmarllqpgarlltmeinpdcaaitqqmlnfaglqdkvtilngasqdl
ipqlkkkydvdtldmvfldhwkdrylpdtlllekcgllrkgtvlladnvivpgtpdflay
vrgsssfecthyssylmkvvdglekaiyqgps

SCOPe Domain Coordinates for d5lr6a_:

Click to download the PDB-style file with coordinates for d5lr6a_.
(The format of our PDB-style files is described here.)

Timeline for d5lr6a_: