Lineage for d5lf3b_ (5lf3 B:)

  1. Root: SCOPe 2.08
  2. 2923792Class d: Alpha and beta proteins (a+b) [53931] (396 folds)
  3. 2988339Fold d.153: Ntn hydrolase-like [56234] (2 superfamilies)
    4 layers: alpha/beta/beta/alpha; has an unusual sheet-to-sheet packing
  4. 2988340Superfamily d.153.1: N-terminal nucleophile aminohydrolases (Ntn hydrolases) [56235] (8 families) (S)
    N-terminal residue provides two catalytic groups, nucleophile and proton donor
  5. 2988529Family d.153.1.4: Proteasome subunits [56251] (4 proteins)
  6. 2988641Protein Proteasome alpha subunit (non-catalytic) [56255] (10 species)
    contains an extension to the common fold at the N-terminus
  7. 2990749Species Human (Homo sapiens) [TaxId:9606] [311422] (15 PDB entries)
  8. 2990774Domain d5lf3b_: 5lf3 B: [321649]
    Other proteins in same PDB: d5lf3d_, d5lf3e_, d5lf3f_, d5lf3g_, d5lf3h_, d5lf3i_, d5lf3j_, d5lf3k_, d5lf3l_, d5lf3m_, d5lf3n1, d5lf3n2, d5lf3r_, d5lf3s_, d5lf3t_, d5lf3u_, d5lf3v_, d5lf3w_, d5lf3x_, d5lf3y_, d5lf3z_
    automated match to d1iruc_
    complexed with 1pe, bo2, cl, k, mg

Details for d5lf3b_

PDB Entry: 5lf3 (more details), 2.1 Å

PDB Description: human 20s proteasome complex with bortezomib at 2.1 angstrom
PDB Compounds: (B:) Proteasome subunit alpha type-4

SCOPe Domain Sequences for d5lf3b_:

Sequence; same for both SEQRES and ATOM records: (download)

>d5lf3b_ d.153.1.4 (B:) Proteasome alpha subunit (non-catalytic) {Human (Homo sapiens) [TaxId: 9606]}
srrydsrttifspegrlyqveyameaighagtclgilandgvllaaerrnihklldevff
sekiyklnedmacsvagitsdanvltnelrliaqryllqyqepipceqlvtalcdikqay
tqfggkrpfgvsllyigwdkhygfqlyqsdpsgnyggwkatcignnsaaavsmlkqdyke
gemtlksalalaikvlnktmdvsklsaekveiatltrengktvirvlkqkeveqlikkhe
eeeakaer

SCOPe Domain Coordinates for d5lf3b_:

Click to download the PDB-style file with coordinates for d5lf3b_.
(The format of our PDB-style files is described here.)

Timeline for d5lf3b_: