SCOPe 2.06: Domain d5g55a4: 5g55 A:726-1094

Lineage for d5g55a4 (5g55 A:726-1094)

1. Root: SCOPe 2.06

2. Class d: Alpha and beta proteins (a+b) [53931] (385 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.0: automated matches [191359] (1 protein)
   not a true family

6. Protein automated matches [190417] (25 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [187294] (882 PDB entries)

8. Domain d5g55a4: 5g55 A:726-1094 [320400]
   Other proteins in same PDB: d5g55a1, d5g55a2, d5g55a3
   automated match to d1he8a4
   complexed with 3qh, so4

Details for d5g55a4

PDB Entry: 5g55, 2.45 Å

PDB Description: 3-quinoline carboxamides inhibitors of pi3k

PDB Compounds: (A:) Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform

SCOPe Domain Sequences for d5g55a4:

Sequence, based on SEQRES records:

>d5g55a4 d.144.1.0 (A:726-1094) automated matches {Human (Homo sapiens) [TaxId: 9606]}
tamlhdftqqvqviemlqkvtldikslsaekydvssqvisqlkqklenlqnsqlpesfrv
pydpglkagalaiekckvmaskkkplwlefkcadptalsnetigiifkhgddlrqdmlil
qilrimesiwetesldlcllpygcistgdkigmieivkdattiakiqqstvgntgafkde
vlnhwlkekspteekfqaaverfvyscagycvatfvlgigdrhndnimitetgnlfhidf
ghilgnyksflginkervpfvltpdflfvmgtsgkktsphfqkfqdicvkaylalrhhtn
lliilfsmmlmtgmpqltskedieyirdaltvgkneedakkyfldqievcrdkgwtvqfn
wflhlvlgi

Sequence, based on observed residues (ATOM records):

>d5g55a4 d.144.1.0 (A:726-1094) automated matches {Human (Homo sapiens) [TaxId: 9606]}
tamlhdftqqvqviemlqkvtldikslsaekydvssqvisqlkqklenlqnsqlpesfrv
pydpglkagalaiekckvmaskkkplwlefkcadptalsnetigiifkhgddlrqdmlil
qilrimesiwetesldlcllpygcistgdkigmieivkdattiakiqqstvgntgafkde
vlnhwlkekspteekfqaaverfvyscagycvatfvlgigdrhndnimitetgnlfhidf
ghilgnervpfvltpdflfvmgtsgkktsphfqkfqdicvkaylalrhhtnlliilfsmm
lmtgmpqltskedieyirdaltvgkneedakkyfldqievcrdkgwtvqfnwflhlvlgi

Timeline for d5g55a4:

• d5g55a4 is new in SCOPe 2.06-stable
  
• d5g55a4 appears in SCOPe 2.07
  
• d5g55a4 appears in the current release, SCOPe 2.08