SCOPe 2.08: Domain d5lc1b1: 5lc1 B:3-321

Lineage for d5lc1b1 (5lc1 B:3-321)

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.2: NAD(P)-binding Rossmann-fold domains [51734] (1 superfamily)
   core: 3 layers, a/b/a; parallel beta-sheet of 6 strands, order 321456
   The nucleotide-binding modes of this and the next two folds/superfamilies are similar

4. Superfamily c.2.1: NAD(P)-binding Rossmann-fold domains [51735] (13 families)

5. Family c.2.1.0: automated matches [191313] (1 protein)
   not a true family

6. Protein automated matches [190069] (319 species)
   not a true protein

7. Species Trypanosome (Trypanosoma brucei) [TaxId:5691] [226760] (22 PDB entries)

8. Domain d5lc1b1: 5lc1 B:3-321 [320232]
   Other proteins in same PDB: d5lc1a2, d5lc1b2, d5lc1c2, d5lc1d2, d5lc1e2, d5lc1f2
   automated match to d4yraa_
   complexed with act, bme, na, nad, pyr

Details for d5lc1b1

PDB Entry: 5lc1, 2.1 Å

PDB Description: l-threonine dehydrogenase from trypanosoma brucei with nad and the inhibitor pyruvate bound.

PDB Compounds: (B:) L-threonine 3-dehydrogenase

SCOPe Domain Sequences for d5lc1b1:

Sequence; same for both SEQRES and ATOM records:

>d5lc1b1 c.2.1.0 (B:3-321) automated matches {Trypanosome (Trypanosoma brucei) [TaxId: 5691]}
prvlvtgalgqigtdlslalrdkfgadsvlvsdvvepgakhplaglkgvekldcldsngf
eklvkefkptwmyhlpaimsvrgeaepdlamdinvnttryalelarkynirifipstiaa
fgdkcgktmtkddtimnpstvygvtkvytellgtwyrqkygvdfrsvrlpgiisaatlpg
ggatdyaihmyhsallqkkcvcpvlpyeslpmmympdtlnslvkimeaplekltrtvyni
tgfsfspselrfsierctdrtieveyvegpaqkianswpdslddsnarndwghqvkydid
mmsedmlrqipilhglpsl

Timeline for d5lc1b1:

• d5lc1b1 first appeared in SCOPe 2.06
  
• d5lc1b1 appears in SCOPe 2.07