SCOPe 2.07: Domain d1he1c1: 1he1 C:2-176

Lineage for d1he1c1 (1he1 C:2-176)

1. Root: SCOPe 2.07

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.37: P-loop containing nucleoside triphosphate hydrolases [52539] (1 superfamily)
   3 layers: a/b/a, parallel or mixed beta-sheets of variable sizes

4. Superfamily c.37.1: P-loop containing nucleoside triphosphate hydrolases [52540] (26 families)
   division into families based on beta-sheet topologies

5. Family c.37.1.8: G proteins [52592] (80 proteins)
   core: mixed beta-sheet of 6 strands, order 231456; strand 2 is antiparallel to the rest

6. Protein Rac [52595] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [52596] (41 PDB entries)

8. Domain d1he1c1: 1he1 C:2-176 [32003]
   Other proteins in same PDB: d1he1a1, d1he1a2, d1he1b1, d1he1b2, d1he1c2, d1he1d2
   rac1 in complex with the GAP domain of ExoS
   complexed with af3, gdp, mg, ni

Details for d1he1c1

PDB Entry: 1he1, 2 Å

PDB Description: crystal structure of the complex between the gap domain of the pseudomonas aeruginosa exos toxin and human rac

PDB Compounds: (C:) ras-related c3 botulinum toxin substrate 1

SCOPe Domain Sequences for d1he1c1:

Sequence; same for both SEQRES and ATOM records:

>d1he1c1 c.37.1.8 (C:2-176) Rac {Human (Homo sapiens) [TaxId: 9606]}
qaikcvvvgdgavgktcllisyttnafpgeyiptvfdnysanvmvdgkpvnlglwdtagq
edydrlrplsypqtdvflicfslvspasfenvrakwypevrhhcpntpiilvgtkldlrd
dkdtieklkekkltpitypqglamakeigavkylecsaltqrglktvfdeairav

Timeline for d1he1c1:

• d1he1c1 first appeared (with stable ids) in SCOP 1.55, called d1he1c_
  
• d1he1c1 appears in SCOPe 2.06
  
• d1he1c1 appears in the current release, SCOPe 2.08