SCOPe 2.08: Domain d5dr2a1: 5dr2 A:128-390

Lineage for d5dr2a1 (5dr2 A:128-390)

1. Root: SCOPe 2.08

2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.7: Protein kinases, catalytic subunit [88854] (66 proteins)
   members organized in the groups and subfamiles specified by the comments

6. Protein Aurora-related kinase 1 (aurora-2) [90038] (1 species)
   OPK group; AIRK subfamily; serine/threonine kinase

7. Species Human (Homo sapiens) [TaxId:9606] [90039] (72 PDB entries)

8. Domain d5dr2a1: 5dr2 A:128-390 [319730]
   Other proteins in same PDB: d5dr2a2
   automated match to d3h10a_
   complexed with 5e1, atp, mg

Details for d5dr2a1

PDB Entry: 5dr2, 2.46 Å

PDB Description: aurora a kinase in complex with aa30 and atp in space group p6122

PDB Compounds: (A:) Aurora kinase A

SCOPe Domain Sequences for d5dr2a1:

Sequence; same for both SEQRES and ATOM records:

>d5dr2a1 d.144.1.7 (A:128-390) Aurora-related kinase 1 (aurora-2) {Human (Homo sapiens) [TaxId: 9606]}
waledfeigrplgkgkfgnvylarekqskfilalkvlfkaqlekagvehqlrreveiqsh
lrhpnilrlygyfhdatrvylileyaplgtvyrelqklskfdeqrtatyitelanalsyc
hskrvihrdikpenlllgsagelkiadfgwsvhapssrratlcgtldylppemiegrmhd
ekvdlwslgvlcyeflvgkppfeantyqetykrisrveftfpdfvtegardlisrllkhn
psqrpmlrevlehpwitansskp

Timeline for d5dr2a1:

• d5dr2a1 first appeared in SCOPe 2.06
  
• d5dr2a1 appears in SCOPe 2.07