SCOPe 2.08: Domain d5hu9a1: 5hu9 A:229-499

Lineage for d5hu9a1 (5hu9 A:229-499)

1. Root: SCOPe 2.08

2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.7: Protein kinases, catalytic subunit [88854] (66 proteins)
   members organized in the groups and subfamiles specified by the comments

6. Protein automated matches [190091] (20 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [188447] (850 PDB entries)

8. Domain d5hu9a1: 5hu9 A:229-499 [319571]
   Other proteins in same PDB: d5hu9a2
   automated match to d3kf4b_
   complexed with 66k, cl, edo

Details for d5hu9a1

PDB Entry: 5hu9, 1.53 Å

PDB Description: crystal structure of abl1 in complex with chmfl-074

PDB Compounds: (A:) Tyrosine-protein kinase ABL1

SCOPe Domain Sequences for d5hu9a1:

Sequence, based on SEQRES records:

>d5hu9a1 d.144.1.7 (A:229-499) automated matches {Human (Homo sapiens) [TaxId: 9606]}
spnydkwemertditmkhklgggqygevyegvwkkysltvavktlkedtmeveeflkeaa
vmkeikhpnlvqllgvctreppfyiitefmtygnlldylrecnrqevnavvllymatqis
sameylekknfihrdlaarnclvgenhlvkvadfglsrlmtgdtytahagakfpikwtap
eslaynkfsiksdvwafgvllweiatygmspypgidlsqvyellekdyrmerpegcpekv
yelmracwqwnpsdrpsfaeihqafetmfqe

Sequence, based on observed residues (ATOM records):

>d5hu9a1 d.144.1.7 (A:229-499) automated matches {Human (Homo sapiens) [TaxId: 9606]}
spnydkwemertditmkhklgggqygevyegvwkkysltvavktlkedtmeveeflkeaa
vmkeikhpnlvqllgvctreppfyiitefmtygnlldylrecnrqevnavvllymatqis
sameylekknfihrdlaarnclvgenhlvkvadfglsrlmtahagakfpikwtapeslay
nkfsiksdvwafgvllweiatygmspypgidlsqvyellekdyrmerpegcpekvyelmr
acwqwnpsdrpsfaeihqafetmfqe

Timeline for d5hu9a1:

• d5hu9a1 first appeared in SCOPe 2.06
  
• d5hu9a1 appears in SCOPe 2.07