SCOPe 2.08: Domain d1nsta_: 1nst A:

Lineage for d1nsta_ (1nst A:)

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.37: P-loop containing nucleoside triphosphate hydrolases [52539] (1 superfamily)
   3 layers: a/b/a, parallel or mixed beta-sheets of variable sizes

4. Superfamily c.37.1: P-loop containing nucleoside triphosphate hydrolases [52540] (27 families)
   division into families based on beta-sheet topologies

5. Family c.37.1.5: PAPS sulfotransferase [52575] (15 proteins)
   Pfam PF00685
   similar to the nucleotide/nucleoside kinases but transfer sulphate group

6. Protein Heparan sulfate N-deacetylase/N-sulfotransferase domain [52582] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [52583] (1 PDB entry)

8. Domain d1nsta_: 1nst A: [31951]
   complexed with a3p

Details for d1nsta_

PDB Entry: 1nst, 2.3 Å

PDB Description: the sulfotransferase domain of human haparin sulfate n-deacetylase/n- sulfotransferase

PDB Compounds: (A:) heparan sulfate n-deacetylase/n-sulfotransferase

SCOPe Domain Sequences for d1nsta_:

Sequence, based on SEQRES records:

>d1nsta_ c.37.1.5 (A:) Heparan sulfate N-deacetylase/N-sulfotransferase domain {Human (Homo sapiens) [TaxId: 9606]}
dplwqdpcedkrhkdiwskektcdrfpklliigpqktgttalylflgmhpdlssnypsse
tfeeiqffnghnyhkgidwymeffpipsnttsdfyfeksanyfdsevaprraaallpkak
vltilinpadrayswyqhqrahddpvalkytfhevitagsdassklralqnrclvpgwya
thierwlsayhanqilvldgkllrtepakvmdmvqkflgvtntidyhktlafdpkkgfwc
qlleggktkclgkskgrkypemdldsraflkdyyrdhnielskllykmgqtlptwlredl
q

Sequence, based on observed residues (ATOM records):

>d1nsta_ c.37.1.5 (A:) Heparan sulfate N-deacetylase/N-sulfotransferase domain {Human (Homo sapiens) [TaxId: 9606]}
dplwqdpccdrfpklliigpqktgttalylflgmhpdlssnypssetfeeiqffnghnyh
kgidwymeffpisdfyfeksanyfdsevaprraaallpkakvltilinpadrayswyqhq
rahddpvalkytfhevitagsdassklralqnrclvpgwyathierwlsayhanqilvld
gkllrtepakvmdmvqkflgvtntidyhktlafdpkkgfwcqlleggktkclgkskgrky
pemdldsraflkdyyrdhnielskllykmgqtlptwlredlq

Timeline for d1nsta_:

• d1nsta_ first appeared (with stable ids) in SCOP 1.55
  
• d1nsta_ appears in SCOPe 2.07