SCOP 1.65: Domain d1efhb_: 1efh B:

Lineage for d1efhb_ (1efh B:)

1. Root: SCOP 1.65

2. Class c: Alpha and beta proteins (a/b) [51349] (121 folds)

3. Fold c.37: P-loop containing nucleoside triphosphate hydrolases [52539] (1 superfamily)
   3 layers: a/b/a, parallel or mixed beta-sheets of variable sizes

4. Superfamily c.37.1: P-loop containing nucleoside triphosphate hydrolases [52540] (21 families)
   division into families based on beta-sheet topologies

5. Family c.37.1.5: PAPS sulfotransferase [52575] (5 proteins)
   similar to the nucleotide/nucleoside kinases but transfer sulphate group

6. Protein Hydroxysteroid sulfotransferase [52578] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [52579] (2 PDB entries)

8. Domain d1efhb_: 1efh B: [31949]
   complexed with a3p

Details for d1efhb_

PDB Entry: 1efh, 2.4 Å

PDB Description: crystal structure of the human hydroxysteroid sulfotransferase in the presence of pap

SCOP Domain Sequences for d1efhb_:

Sequence, based on SEQRES records:

>d1efhb_ c.37.1.5 (B:) Hydroxysteroid sulfotransferase {Human (Homo sapiens)}
dflwfegiafptmgfrsetlrkvrdefvirdedviiltypksgtnwlaeilclmhskgda
kwiqsvpiwerspwveseigytalsetesprlfsshlpiqlfpksffsskakviylmrnp
rdvlvsgyffwknmkfikkpksweeyfewfcqgtvlygswfdhihgwmpmreeknfllls
yeelkqdtgrtiekicqflgktlepeelnlilknssfqsmkenkmsnysllsvdyvvdka
qllrkgvsgdwknhftvaqaedfdklfqekmadlprklaaaleh

Sequence, based on observed residues (ATOM records):

>d1efhb_ c.37.1.5 (B:) Hydroxysteroid sulfotransferase {Human (Homo sapiens)}
dflwfegiafptmgfrsetlrkvrdefvirdedviiltypksgtnwlaeilclmhskgda
kwiqsvpiwerspwveseigytalsetesprlfsshlpiqlfpksffsskakviylmrnp
rdvlvsgyffwknmkfikkpksweeyfewfcqgtvlygswfdhihgwmpmreeknfllls
yeelkqdtgrtiekicqflgktlepeelnlilknssfqsmkenkmsnysllsvdyvkaql
lrkgvsgdwknhftvaqaedfdklfqekmadlprklaaaleh

Timeline for d1efhb_:

• d1efhb_ first appeared (with stable ids) in SCOP 1.55
  
• d1efhb_ appears in SCOP 1.63
  
• d1efhb_ appears in SCOP 1.67
  
• d1efhb_ appears in the current release, SCOPe 2.08, called d1efhb1