SCOPe 2.06: Domain d5k14b_: 5k14 B:

Lineage for d5k14b_ (5k14 B:)

1. Root: SCOPe 2.06

2. Class e: Multi-domain proteins (alpha and beta) [56572] (69 folds)

3. Fold e.8: DNA/RNA polymerases [56671] (1 superfamily)
   divided into morphological domains including "palm", "thumb" and "fingers"; the catalytic "palm" domain is conserved to all members

4. Superfamily e.8.1: DNA/RNA polymerases [56672] (7 families)
   "palm" domain has a ferredoxin-like fold, related to that of an adenylyl cyclase domain

5. Family e.8.1.2: Reverse transcriptase [56686] (3 proteins)

6. Protein HIV-1 reverse transcriptase [56689] (4 species)

7. Species Human immunodeficiency virus type 1 group m subtype b (isolate lw123) [TaxId:82834] [319106] (1 PDB entry)

8. Domain d5k14b_: 5k14 B: [319107]
   Other proteins in same PDB: d5k14a2
   automated match to d1rt1b1
   complexed with ib1

Details for d5k14b_

PDB Entry: 5k14, 2.4 Å

PDB Description: hiv-1 reverse transcriptase in complex with a 2,6-difluorophenyl dapy analog

PDB Compounds: (B:) HIV-1 reverse transcriptase (isolate LW123)

SCOPe Domain Sequences for d5k14b_:

Sequence, based on SEQRES records:

>d5k14b_ e.8.1.2 (B:) HIV-1 reverse transcriptase {Human immunodeficiency virus type 1 group m subtype b (isolate lw123) [TaxId: 82834]}
etvpvklkpgmdgpkvkqwplteekikalveictemekegkiskigpenpyntpvfaikk
kdstkwrklvdfrelnkrtqdfwevqlgiphpaglkkkksvtvldvgdayfsvpldedfr
kytaftipsinnetpgiryqynvlpqgwkgspaifqssmtkilepfrkqnpdiviyqymd
dlyvgsdleigqhrtkieelrqhllrwglttpdkkhqkeppflwmgyelhpdkwtvqpiv
lpekdswtvndiqklvgklnwasqiypgikvrqlckllrgtkalteviplteeaelelae
nreilkepvhgvyydpskdliaeiqkqgqgqwtyqiyqepfknlktgkyarmrgahtndv
kqlteavqkittesiviwgktpkfklpiqketwetwwteywqatwipewefvntpplvkl
wyql

Sequence, based on observed residues (ATOM records):

>d5k14b_ e.8.1.2 (B:) HIV-1 reverse transcriptase {Human immunodeficiency virus type 1 group m subtype b (isolate lw123) [TaxId: 82834]}
etvpvklkpgmdgpkvkqwplteekikalveictemekegkiskigpenpyntpvfaikk
stkwrklvdfrelnkrtqdfwevqlgiphpaglkkkksvtvldvgdayfsvpldedfrky
taftipsinnetpgiryqynvlpqgwkgspaifqssmtkilepfrkqnpdiviyqymddl
yvgsdleigqhrtkieelrqhllrwgltyelhpdkwtvqpivlpekdswtvndiqklvgk
lnwasqiypgikvrqlckllrgtkalteviplteeaelelaenreilkepvhgvyydpsk
dliaeiqkqgqgqwtyqiyqepfknlktgkyartndvkqlteavqkittesiviwgktpk
fklpiqketwetwwteywqatwipewefvntpplvklwyql

Timeline for d5k14b_:

• d5k14b_ is new in SCOPe 2.06-stable
  
• d5k14b_ appears in SCOPe 2.07
  
• d5k14b_ appears in the current release, SCOPe 2.08