SCOPe 2.08: Domain d5i4vf_: 5i4v F:

Lineage for d5i4vf_ (5i4v F:)

1. Root: SCOPe 2.08

2. Class a: All alpha proteins [46456] (290 folds)

3. Fold a.123: Nuclear receptor ligand-binding domain [48507] (1 superfamily)
   multihelical; 3 layers or orthogonally packed helices

4. Superfamily a.123.1: Nuclear receptor ligand-binding domain [48508] (2 families)

5. Family a.123.1.1: Nuclear receptor ligand-binding domain [48509] (34 proteins)

6. Protein automated matches [190059] (14 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [187214] (171 PDB entries)

8. Domain d5i4vf_: 5i4v F: [319018]
   Other proteins in same PDB: d5i4vb2
   automated match to d4j5xc_
   complexed with 67s

Details for d5i4vf_

PDB Entry: 5i4v, 2.61 Å

PDB Description: discovery of novel, orally efficacious liver x receptor (lxr) beta agonists

PDB Compounds: (F:) Retinoic acid receptor RXR-beta,Nuclear receptor coactivator 2

SCOPe Domain Sequences for d5i4vf_:

Sequence, based on SEQRES records:

>d5i4vf_ a.123.1.1 (F:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
eempvdrileaelaveqksdqgvegpggtggsgsspndpvtnicqaadkqlftlvewakr
iphfsslplddqvillragwnelliasfshrsidvrdgillatglhvhrnsahsagvgai
fdrvltelvskmrdmrmdktelgclraiilfnpdakglsnpsevevlrekvyasletyck
qkypeqqgrfaklllrlpalrsiglkclehlfffkligdtpidtflmemleagsgsgshk
ilhrllqd

Sequence, based on observed residues (ATOM records):

>d5i4vf_ a.123.1.1 (F:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
eempvdrileaelavepvtnicqaadkqlftlvewakriphfsslplddqvillragwne
lliasfshrsidvrdgillatglhvhrnsahsagvgaifdrvltelvskmrdmrmdktel
gclraiilfnpdakglsnpsevevlrekvyasletyckqkypeqqgrfaklllrlpalrs
iglkclehlfffkligdtflmemleagshkilhrllqd

Timeline for d5i4vf_:

• d5i4vf_ first appeared in SCOPe 2.06
  
• d5i4vf_ appears in SCOPe 2.07