SCOPe 2.08: Domain d5juwa_: 5juw A:

Lineage for d5juwa_ (5juw A:)

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.66: S-adenosyl-L-methionine-dependent methyltransferases [53334] (1 superfamily)
   core: 3 layers, a/b/a; mixed beta-sheet of 7 strands, order 3214576; strand 7 is antiparallel to the rest

4. Superfamily c.66.1: S-adenosyl-L-methionine-dependent methyltransferases [53335] (61 families)

5. Family c.66.1.31: Catalytic, N-terminal domain of histone methyltransferase Dot1l [89746] (2 proteins)

6. Protein automated matches [191247] (1 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [189737] (31 PDB entries)

8. Domain d5juwa_: 5juw A: [318830]
   automated match to d4hraa_
   complexed with 6nr, unx

Details for d5juwa_

PDB Entry: 5juw, 2.28 Å

PDB Description: complex of dot1l with ss148

PDB Compounds: (A:) Histone-lysine N-methyltransferase, H3 lysine-79 specific

SCOPe Domain Sequences for d5juwa_:

Sequence, based on SEQRES records:

>d5juwa_ c.66.1.31 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
klelrlkspvgaepavypwplpvydkhhdaaheiietirwvceeipdlklamenyvlidy
dtksfesmqrlcdkynraidsihqlwkgttqpmklntrpstgllrhilqqvynhsvtdpe
klnnyepfspevygetsfdlvaqmideikmtdddlfvdlgsgvgqvvlqvaaatnckhhy
gvekadipakyaetmdrefrkwmkwygkkhaeytlergdflseewreriantsvifvnnf
afgpevdhqlkerfanmkeggrivsskpfaplnfrinsrnlsdigtimrvvelsplkgsv
swtgkpvsyylhtidrtilenyfsslknp

Sequence, based on observed residues (ATOM records):

>d5juwa_ c.66.1.31 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
klelrlkspvgaepavypwplpvydkhhdaaheiietirwvceeipdlklamenydtksf
esmqrlcdkynraidsihqlwkgttqpmklntrpstgllrhilqqvynhsvtdpeklnny
epfspevygetsfdlvaqmideikmtdddlfvdlgsgvgqvvlqvaaatnckhhygveka
dipakyaetmdrefrkwmkwygkkhaeytlergdflseewreriantsvifvnnfafgpe
vdhqlkerfanmkeggrivsskpfaplnfrinsrnlsdigtimrvvelsplkgsvswtgk
pvsyylhtidrtilenyfsslknp

Timeline for d5juwa_:

• d5juwa_ first appeared in SCOPe 2.06
  
• d5juwa_ appears in SCOPe 2.07