SCOPe 2.06: Domain d5a4bb2: 5a4b B:149-257

Lineage for d5a4bb2 (5a4b B:149-257)

1. Root: SCOPe 2.06

2. Class a: All alpha proteins [46456] (289 folds)

3. Fold a.40: CH domain-like [47575] (3 superfamilies)
   core: 4 helices: bundle

4. Superfamily a.40.1: Calponin-homology domain, CH-domain [47576] (2 families)

5. Family a.40.1.0: automated matches [227151] (1 protein)
   not a true family

6. Protein automated matches [226856] (3 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [224978] (30 PDB entries)

8. Domain d5a4bb2: 5a4b B:149-257 [318752]
   automated match to d1tjta2
   mutant

Details for d5a4bb2

PDB Entry: 5a4b, 2.01 Å

PDB Description: mutations in the calponin homology domain of alpha-actinin-2 affect actin binding and incorporation in muscle.

PDB Compounds: (B:) human alpha-actinin-2

SCOPe Domain Sequences for d5a4bb2:

Sequence; same for both SEQRES and ATOM records:

>d5a4bb2 a.40.1.0 (B:149-257) automated matches {Human (Homo sapiens) [TaxId: 9606]}
eetsakeglllwcqrktapyrnvniqnfhtswkdglglcalihrhrpdlidysklnkddp
igninlameiaekhldipkmldaedivntpkpderaimtyvscfyhafa

Timeline for d5a4bb2:

• d5a4bb2 is new in SCOPe 2.06-stable
  
• d5a4bb2 appears in SCOPe 2.07
  
• d5a4bb2 appears in the current release, SCOPe 2.08