Lineage for d5j1ed_ (5j1e D:)

  1. Root: SCOPe 2.06
  2. 2243857Class e: Multi-domain proteins (alpha and beta) [56572] (69 folds)
  3. 2246832Fold e.8: DNA/RNA polymerases [56671] (1 superfamily)
    divided into morphological domains including "palm", "thumb" and "fingers"; the catalytic "palm" domain is conserved to all members
  4. 2246833Superfamily e.8.1: DNA/RNA polymerases [56672] (7 families) (S)
    "palm" domain has a ferredoxin-like fold, related to that of an adenylyl cyclase domain
  5. 2247182Family e.8.1.2: Reverse transcriptase [56686] (3 proteins)
  6. 2247183Protein HIV-1 reverse transcriptase [56689] (4 species)
  7. 2247227Species Human immunodeficiency virus type 1 [TaxId:11676] [56690] (172 PDB entries)
    Uniprot P04585 159-692 # chain A coverage; chain B is shorter: 162-582 ! Uniprot P03366 186-725 # chain A coverage; chain B coverage: 156-584 ! Uniprot P04585 158-698 # chain A coverage; chain B is shorter: 159-595
  8. 2247507Domain d5j1ed_: 5j1e D: [318504]
    Other proteins in same PDB: d5j1ea2, d5j1eb2, d5j1ec2
    automated match to d2hmib_
    complexed with 6ft, mg

Details for d5j1ed_

PDB Entry: 5j1e (more details), 2.9 Å

PDB Description: crystal structure of a hydroxypyridone carboxylic acid active-site rnase h inhibitor in complex with hiv reverse transcriptase
PDB Compounds: (D:) hiv-1 reverse transcriptase p51 domain

SCOPe Domain Sequences for d5j1ed_:

Sequence, based on SEQRES records: (download)

>d5j1ed_ e.8.1.2 (D:) HIV-1 reverse transcriptase {Human immunodeficiency virus type 1 [TaxId: 11676]}
tvpvklkpgmdgpkvkqwplteekikalveictemekegkiskigpenpyntpvfaikkk
dstkwrklvdfrelnkrtqdfwevqlgiphpaglkkkksvtvldvgdayfsvpldedfrk
ytaftipsinnetpgiryqynvlpqgwkgspaifqssmtkilepfkkqnpdiviyqymdd
lyvgsdleigqhrtkieelrqhllrwglttpdkkhqkeppflwmgyelhpdkwtvqpivl
pekdswtvndiqklvgklnwasqiypgikvrqlskllrgtkalteviplteeaelelaen
reilkepvhgvyydpskdliaeiqkqgqgqwtyqiyqepfknlktgkyarmrgahtndvk
qlteavqkittesiviwgktpkfklpiqketwetwwteywqatwipewefvntpplvklw
y

Sequence, based on observed residues (ATOM records): (download)

>d5j1ed_ e.8.1.2 (D:) HIV-1 reverse transcriptase {Human immunodeficiency virus type 1 [TaxId: 11676]}
tvpvklkpgmdgpkvkqwplteekikalveictemekegkiskigpenpyntpvfaikks
tkwrklvdfrelnkrtqdflgiphpaglkkkksvtvldvgdayfsvpldedfrkytafti
psinnetpgiryqynvlpqgwkgspaifqssmtkilepfkkqnpdiviyqymddlyvgsd
leigqhrtkieelrqhllrwgltgyelhpdkwtvqpivlpekdswtvndiqklvgklnwa
sqiypgikvrqlskllrgtkalteviplteeaelelaenreilkepvhgvyydpskdlia
eiqkqgqgqwtyqiyqepfknlktgkyandvkqlteavqkittesiviwgktpkfklpiq
ketwetwwteywqatwipewefvntpplvklwy

SCOPe Domain Coordinates for d5j1ed_:

Click to download the PDB-style file with coordinates for d5j1ed_.
(The format of our PDB-style files is described here.)

Timeline for d5j1ed_: