SCOPe 2.08: Domain d5k0zd1: 5k0z D:1-159

Lineage for d5k0zd1 (5k0z D:1-159)

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.2: NAD(P)-binding Rossmann-fold domains [51734] (1 superfamily)
   core: 3 layers, a/b/a; parallel beta-sheet of 6 strands, order 321456
   The nucleotide-binding modes of this and the next two folds/superfamilies are similar

4. Superfamily c.2.1: NAD(P)-binding Rossmann-fold domains [51735] (13 families)

5. Family c.2.1.5: LDH N-terminal domain-like [51848] (9 proteins)

6. Protein Lactate dehydrogenase [51859] (19 species)

7. Species Chicken (Gallus gallus) [TaxId:9031] [318259] (1 PDB entry)

8. Domain d5k0zd1: 5k0z D:1-159 [318264]
   Other proteins in same PDB: d5k0za2, d5k0zb2, d5k0zc2, d5k0zd2
   automated match to d1i0za1

Details for d5k0zd1

PDB Entry: 5k0z, 2.8 Å

PDB Description: cryo-em structure of lactate dehydrogenase (ldh) in inhibitor-bound state

PDB Compounds: (D:) L-lactate dehydrogenase B chain

SCOPe Domain Sequences for d5k0zd1:

Sequence, based on SEQRES records:

>d5k0zd1 c.2.1.5 (D:1-159) Lactate dehydrogenase {Chicken (Gallus gallus) [TaxId: 9031]}
atlkeklitpvaagstvpsnkitvvgvgqvgmacaisilgkglcdelalvdvledklkge
mmdlqhgslflqthkivadkdyavtanskivvvtagvrqqegesrlnlvqrnvnvfkfii
pqivkyspnctilvvsnpvdiltyvtwklsglpkhrvig

Sequence, based on observed residues (ATOM records):

>d5k0zd1 c.2.1.5 (D:1-159) Lactate dehydrogenase {Chicken (Gallus gallus) [TaxId: 9031]}
atlkeklitpvtvpsnkitvvgvgqvgmacaisilgkglcdelalvdvledklkgemmdl
qhgslflqthkivadkdyavtanskivvvtagvlvqrnvnvfkfiipqivkyspnctilv
vsnpvdiltyvtwklsglpkhrvig

Timeline for d5k0zd1:

• d5k0zd1 first appeared in SCOPe 2.06
  
• d5k0zd1 appears in SCOPe 2.07