SCOPe 2.08: Domain d5jaga_: 5jag A:

Lineage for d5jaga_ (5jag A:)

1. Root: SCOPe 2.08

2. Class f: Membrane and cell surface proteins and peptides [56835] (69 folds)

3. Fold f.54: SNF-like [161069] (1 superfamily)
   12 transmembrane helices; duplication: consists of two structurally similar halves

4. Superfamily f.54.1: SNF-like [161070] (3 families)

5. Family f.54.1.1: SNF-like [161071] (2 proteins)
   Pfam PF00209; Sodium:neurotransmitter symporter

6. Protein Na(+):neurotransmitter symporter homologue LeuT [161072] (1 species)

7. Species Aquifex aeolicus [TaxId:63363] [161073] (43 PDB entries)
   Uniprot O67854 5-513

8. Domain d5jaga_: 5jag A: [318039]
   automated match to d4hmka_
   complexed with bog; mutant

Details for d5jaga_

PDB Entry: 5jag, 2.58 Å

PDB Description: leut t354h mutant in the outward-oriented, na+-free return state

PDB Compounds: (A:) Transporter

SCOPe Domain Sequences for d5jaga_:

Sequence, based on SEQRES records:

>d5jaga_ f.54.1.1 (A:) Na(+):neurotransmitter symporter homologue LeuT {Aquifex aeolicus [TaxId: 63363]}
krehwatrlglilamagnavglgnflrfpvqaaengggafmipyiiafllvgiplmwiew
amgryggaqghgttpaifyllwrnrfakilgvfglwiplvvaiyyvyieswtlgfaikfl
vglvpepppnatdpdsilrpfkeflysyigvpkgdepilkpslfayivflitmfinvsil
irgiskgierfakiamptlfilavflvirvflletpngtaadglnflwtpdfeklkdpgv
wiaavgqifftlslgfgaiityasyvrkdqdivlsgltaatlnekaevilggsisipaav
affgvanavaiakagafnlgfitlpaifsqtaggtflgflwffllffaglhssiaimqpm
iafledelklsrkhavlwtaaivffsahlvmflnksldemdfwagtigvvffglteliif
fwifgadkaweeinrggiikvpriyyyvmryitpaflavllvvwareyipkimeethwtv
witrfyiiglflfltflvflaerr

Sequence, based on observed residues (ATOM records):

>d5jaga_ f.54.1.1 (A:) Na(+):neurotransmitter symporter homologue LeuT {Aquifex aeolicus [TaxId: 63363]}
krehwatrlglilamagnavglgnflrfpvqaaengggafmipyiiafllvgiplmwiew
amgryggaqghgttpaifyllwrnrfakilgvfglwiplvvaiyyvyieswtlgfaikfl
vglvpepptdpdsilrpfkeflysyigvpkgdepilkpslfayivflitmfinvsilirg
iskgierfakiamptlfilavflvirvflletpngtaadglnflwtpdfeklkdpgvwia
avgqifftlslgfgaiityasyvrkdqdivlsgltaatlnekaevilggsisipaavaff
gvanavaiakagafnlgfitlpaifsqtaggtflgflwffllffaglhssiaimqpmiaf
ledelklsrkhavlwtaaivffsahlvmflnksldemdfwagtigvvffglteliiffwi
fgadkaweeinrggiikvpriyyyvmryitpaflavllvvwareyipthwtvwitrfyii
glflfltflvflaerr

Timeline for d5jaga_:

• d5jaga_ first appeared in SCOPe 2.06
  
• d5jaga_ appears in SCOPe 2.07