SCOPe 2.08: Domain d5iuga_: 5iug A:

Lineage for d5iuga_ (5iug A:)

1. Root: SCOPe 2.08

2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.0: automated matches [191359] (1 protein)
   not a true family

6. Protein automated matches [190417] (37 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [187294] (1476 PDB entries)

8. Domain d5iuga_: 5iug A: [317562]
   automated match to d4fnwa_
   complexed with 729

Details for d5iuga_

PDB Entry: 5iug, 1.93 Å

PDB Description: crystal structure of anaplastic lymphoma kinase (alk) in complex with 5a

PDB Compounds: (A:) ALK tyrosine kinase receptor

SCOPe Domain Sequences for d5iuga_:

Sequence, based on SEQRES records:

>d5iuga_ d.144.1.0 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
npnysfagktssisdlkevprknitlirglghgafgevyegqvsgmpndpsplqvavktl
pevcseqdeldflmealiiskfnhqnivrcigvslqslprfillelmaggdlksflretr
prpsqpsslamldllhvardiacgcqyleenhfihrdiaarnclltcpgpgrvakigdfg
mardiyrasyyrkggcamlpvkwmppeafmegiftsktdtwsfgvllweifslgympyps
ksnqevlefvtsggrmdppkncpgpvyrimtqcwqhqpedrpnfaiilerieyctqdpdv
intalpieygpl

Sequence, based on observed residues (ATOM records):

>d5iuga_ d.144.1.0 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
npnysfagktssisdlkevprknitlirglggevyegqvsplqvavktlpevcseqdeld
flmealiiskfnhqnivrcigvslqslprfillelmaggdlksflretrprpslamldll
hvardiacgcqyleenhfihrdiaarnclltcpgpgrvakigdfgmagcamlpvkwmppe
afmegiftsktdtwsfgvllweifslgympypsksnqevlefvtsggrmdppkncpgpvy
rimtqcwqhqpedrpnfaiilerieyctqdpdvintalpieygpl

Timeline for d5iuga_:

• d5iuga_ first appeared in SCOPe 2.06
  
• d5iuga_ appears in SCOPe 2.07