SCOPe 2.08: Domain d5fppb1: 5fpp B:5-543

Lineage for d5fppb1 (5fpp B:5-543)

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.69: alpha/beta-Hydrolases [53473] (1 superfamily)
   core: 3 layers, a/b/a; mixed beta-sheet of 8 strands, order 12435678, strand 2 is antiparallel to the rest

4. Superfamily c.69.1: alpha/beta-Hydrolases [53474] (43 families)
   many members have left-handed crossover connection between strand 8 and additional strand 9

5. Family c.69.1.1: Acetylcholinesterase-like [53475] (6 proteins)
   automatically mapped to Pfam PF00135

6. Protein Acetylcholinesterase [53476] (6 species)

7. Species Mouse (Mus musculus) [TaxId:10090] [53479] (39 PDB entries)

8. Domain d5fppb1: 5fpp B:5-543 [317257]
   Other proteins in same PDB: d5fppa2, d5fppb2
   automated match to d1maac_
   complexed with ae3, co3, hi6, nag, p6g

Details for d5fppb1

PDB Entry: 5fpp, 2.4 Å

PDB Description: structure of a pre-reaction ternary complex between sarin- acetylcholinesterase and hi-6

PDB Compounds: (B:) acetylcholinesterase

SCOPe Domain Sequences for d5fppb1:

Sequence, based on SEQRES records:

>d5fppb1 c.69.1.1 (B:5-543) Acetylcholinesterase {Mouse (Mus musculus) [TaxId: 10090]}
dpqllvrvrggqlrgirlkapggpvsaflgipfaeppvgsrrfmppepkrpwsgvldatt
fqnvcyqyvdtlypgfegtemwnpnrelsedclylnvwtpyprpasptpvliwiygggfy
sgaasldvydgrflaqvegavlvsmnyrvgtfgflalpgsreapgnvglldqrlalqwvq
eniaafggdpmsvtlfgesagaasvgmhilslpsrslfhravlqsgtpngpwatvsagea
rrratllarlvgcppggaggndteliaclrtrpaqdlvdhewhvlpqesifrfsfvpvvd
gdflsdtpealintgdfqdlqvlvgvvkdegsyflvygvpgfskdneslisraqflagvr
igvpqasdlaaeavvlhytdwlhpedpthlrdamsavvgdhnvvcpvaqlagrlaaqgar
vyayifehrastltwplwmgvphgyeiefifglpldpslnytteerifaqrlmkywtnfa
rtgdpndprdskspqwppyttaaqqyvslnlkplevrrglraqtcafwnrflpkllsat

Sequence, based on observed residues (ATOM records):

>d5fppb1 c.69.1.1 (B:5-543) Acetylcholinesterase {Mouse (Mus musculus) [TaxId: 10090]}
dpqllvrvrggqlrgirlkapggpvsaflgipfaeppvgsrrfmppepkrpwsgvldatt
fqnvcyqyvdtlypgfegtemwnpnrelsedclylnvwtpyprpasptpvliwiygggfy
sgaasldvydgrflaqvegavlvsmnyrvgtfgflalpgsreapgnvglldqrlalqwvq
eniaafggdpmsvtlfgesagaasvgmhilslpsrslfhravlqsgtpngpwatvsagea
rrratllarlvgcndteliaclrtrpaqdlvdhewhvlpqesifrfsfvpvvdgdflsdt
pealintgdfqdlqvlvgvvkdegsyflvygvpgfskdneslisraqflagvrigvpqas
dlaaeavvlhytdwlhpedpthlrdamsavvgdhnvvcpvaqlagrlaaqgarvyayife
hrastltwplwmgvphgyeiefifglpldpslnytteerifaqrlmkywtnfartgdpnd
prdskspqwppyttaaqqyvslnlkplevrrglraqtcafwnrflpkllsat

Timeline for d5fppb1:

• d5fppb1 first appeared in SCOPe 2.06
  
• d5fppb1 appears in SCOPe 2.07