Lineage for d2hgsa1 (2hgs A:202-303)

  1. Root: SCOP 1.63
  2. 235644Class c: Alpha and beta proteins (a/b) [51349] (117 folds)
  3. 242415Fold c.30: PreATP-grasp domain [52439] (1 superfamily)
    3 layers: a/b/a; parallel or mixed beta-sheet of 4 to 6 strands
    possible rudiment form of Rossmann-fold domain
  4. 242416Superfamily c.30.1: PreATP-grasp domain [52440] (5 families) (S)
    preceeds the ATP-grasp domain common to all superfamily members, can contain a substrate-binding function
  5. 242546Family c.30.1.4: Eukaryotic glutathione synthetase, substrate-binding domain [52460] (1 protein)
    circularly permuted version of prokaryotic enzyme
  6. 242547Protein Eukaryotic glutathione synthetase, substrate-binding domain [52461] (2 species)
  7. 242553Species Human (Homo sapiens) [TaxId:9606] [52462] (1 PDB entry)
  8. 242554Domain d2hgsa1: 2hgs A:202-303 [31722]
    Other proteins in same PDB: d2hgsa4
    complexed with adp, gsh, mg, sul

Details for d2hgsa1

PDB Entry: 2hgs (more details), 2.1 Å

PDB Description: human glutathione synthetase

SCOP Domain Sequences for d2hgsa1:

Sequence; same for both SEQRES and ATOM records: (download)

>d2hgsa1 c.30.1.4 (A:202-303) Eukaryotic glutathione synthetase, substrate-binding domain {Human (Homo sapiens)}
pnalvlliaqekernifdqraienellarnihvirrtfedisekgsldqdrrlfvdgqei
avvyfrdgymprqyslqnwearlllershaakcpdiatqlag

SCOP Domain Coordinates for d2hgsa1:

Click to download the PDB-style file with coordinates for d2hgsa1.
(The format of our PDB-style files is described here.)

Timeline for d2hgsa1:

View in 3D
Domains from same chain:
(mouse over for more information)
d2hgsa4