SCOPe 2.06: Domain d4zt7a1: 4zt7 A:238-606

Lineage for d4zt7a1 (4zt7 A:238-606)

1. Root: SCOPe 2.06

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.26: Adenine nucleotide alpha hydrolase-like [52373] (3 superfamilies)
   core: 3 layers, a/b/a ; parallel beta-sheet of 5 strands, order 32145

4. Superfamily c.26.1: Nucleotidylyl transferase [52374] (6 families)

5. Family c.26.1.0: automated matches [191377] (1 protein)
   not a true family

6. Protein automated matches [190459] (50 species)
   not a true protein

7. Species Trypanosoma brucei [TaxId:999953] [226467] (27 PDB entries)

8. Domain d4zt7a1: 4zt7 A:238-606 [317162]
   Other proteins in same PDB: d4zt7a2, d4zt7b2, d4zt7b3
   automated match to d4eg8b1
   protein/RNA complex; complexed with 4rc, dms, gol, met

Details for d4zt7a1

PDB Entry: 4zt7, 2.4 Å

PDB Description: trypanosoma brucei methionyl-trna synthetase in complex with inhibitor n-[(4r)-6,8-dichloro-1,2,3,4-tetrahydroquinolin-4-yl]-n'-(5-fluoro- 3h-imidazo[4,5-b]pyridin-2-yl)propane-1,3-diamine (chem 1717)

PDB Compounds: (A:) Methionyl-tRNA synthetase

SCOPe Domain Sequences for d4zt7a1:

Sequence, based on SEQRES records:

>d4zt7a1 c.26.1.0 (A:238-606) automated matches {Trypanosoma brucei [TaxId: 999953]}
vekvffvtspiyyvnaaphighvystlitdvigryhrvkgervfaltgtdehgqkvaeaa
kqkqvspydfttavagefkkcfeqmdysidyfirttneqhkavvkelwtkleqkgdiylg
ryegwysisdesfltpqnitdgvdkdgnpckvslesghvvtwvseenymfrlsafrerll
ewyhanpgcivpefrrreviravekglpdlsvsraratlhnwaipvpgnpdhcvyvwlda
ltnyltgsrlrvdesgkevslvddfnelerfpadvhvigkdilkfhaiywpafllsaglp
lpkkivahgwwtkdrkkiskslgnvfdpvekaeefgydalkyfllresgfsddgdysdkn
miarlngel

Sequence, based on observed residues (ATOM records):

>d4zt7a1 c.26.1.0 (A:238-606) automated matches {Trypanosoma brucei [TaxId: 999953]}
vekvffvtspiyyvnaaphighvystlitdvigryhrvkgervfaltgtdehgqkvaeaa
kqkqvspydfttavagefkkcfeqmdysidyfirttneqhkavvkelwtkleqkgdiylg
ryegwysisdesfltpqnitdgvdkdgnpckvslesghvvtwvseenymfrlsafrerll
ewyhanpgcivpefrrreviravekglpdlsvsraratlhnwaipvpgnpdhcvyvwlda
ltnyltgsrlrvdesgkevslvddfnelerfpadvhvigkdilkfhaiywpafllsaglp
lpkkivahgwwtknvfdpvekaeefgydalkyfllresgfsddgdysdknmiarlngel

Timeline for d4zt7a1:

• d4zt7a1 is new in SCOPe 2.06-stable
  
• d4zt7a1 appears in SCOPe 2.07
  
• d4zt7a1 appears in the current release, SCOPe 2.08