Lineage for d5edea_ (5ede A:)

  1. Root: SCOPe 2.08
  2. 2685877Class a: All alpha proteins [46456] (290 folds)
  3. 2736615Fold a.211: HD-domain/PDEase-like [109603] (1 superfamily)
    multihelical; consists of two different alpha-helical bundles
  4. 2736616Superfamily a.211.1: HD-domain/PDEase-like [109604] (9 families) (S)
  5. 2737183Family a.211.1.0: automated matches [191566] (1 protein)
    not a true family
  6. 2737184Protein automated matches [190983] (12 species)
    not a true protein
  7. 2737203Species Human (Homo sapiens) [TaxId:9606] [188676] (139 PDB entries)
  8. 2737444Domain d5edea_: 5ede A: [313618]
    Other proteins in same PDB: d5edeb2, d5edeb3, d5eded2
    automated match to d5axqb_
    complexed with 5m6, gol, mg, zn

Details for d5edea_

PDB Entry: 5ede (more details), 2.2 Å

PDB Description: human pde10a in complex with 1-(4-chloro-phenyl)-3-methyl-1h-thieno[2, 3-c]pyrazole-5-carboxylic acid (tetrahydro-furan-2-ylmethyl)-amide at 2.2a
PDB Compounds: (A:) cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A

SCOPe Domain Sequences for d5edea_:

Sequence; same for both SEQRES and ATOM records: (download)

>d5edea_ a.211.1.0 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
qglmqftlpvrlcreielfhfdigpfenmwpgifvymvhrscgtscfeleklcrfimsvk
knyrrvpyhnwkhavtvahcmyailqnnhtlftdlerkglliaclchdldhrgfsnsylq
kfdhplaalyststmeqhhfsqtvsilqleghnifstlssseyeqvleiirkaiiatdla
lyfgnrkqleemyqtgslnlnnqshrdrviglmmtacdlcsvtklwpvtkltandiyaef
waegdemkklgiqpipmmdrdkkdevpqgqlgfynavaipcyttltqilpptepllkacr
dnlsqwekvirgee

SCOPe Domain Coordinates for d5edea_:

Click to download the PDB-style file with coordinates for d5edea_.
(The format of our PDB-style files is described here.)

Timeline for d5edea_: