SCOPe 2.07: Family c.44.3.1: PIWI domain N-terminal

Lineage for Family c.44.3.1: PIWI domain N-terminal

1. Root: SCOPe 2.07

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.44: Phosphotyrosine protein phosphatases I-like [52787] (3 superfamilies)
   3 layers: a/b/a; parallel beta-sheet of 4 strands, order 2134

4. Superfamily c.44.3: PIWI domain N-terminal-like [310581] (2 families)

5. Family c.44.3.1: PIWI domain N-terminal [310609] (4 proteins)
   PubMed 15565169 notes that both halves of PIWI are usually a single evolutionary unit; however, fragments have been characterized separately. The C-terminal half is (c.55.3.10)

Proteins:

1. Argonaute homologue Aq_1447 [310684] (1 species)

   • Species Aquifex aeolicus [TaxId:63363] [310901] (4 PDB entries)

2. Argonaute homologue PF0537 [310686] (1 species)

   • Species Pyrococcus furiosus [TaxId:2261] [310903] (3 PDB entries)

3. Argonaute-2 [310718] (1 species)
   Pfam PF16487

   • Species Human (Homo sapiens) [TaxId:9606] [310964] (12 PDB entries)

4. Hypothetical protein AF1318 [310688] (1 species)

   • Species Archaeoglobus fulgidus [TaxId:2234] [310905] (3 PDB entries)

More info for Family c.44.3.1: PIWI domain N-terminal

Timeline for Family c.44.3.1: PIWI domain N-terminal:

• Family c.44.3.1: PIWI domain N-terminal first appeared in SCOPe 2.06
  
• Family c.44.3.1: PIWI domain N-terminal appears in the current release, SCOPe 2.08