SCOPe 2.07: Domain d5ddaa2: 5dda A:231-587

Lineage for d5ddaa2 (5dda A:231-587)

1. Root: SCOPe 2.07

2. Class a: All alpha proteins [46456] (289 folds)

3. Fold a.118: alpha-alpha superhelix [48370] (28 superfamilies)
   multihelical; 2 (curved) layers: alpha/alpha; right-handed superhelix

4. Superfamily a.118.8: TPR-like [48452] (10 families)

5. Family a.118.8.1: Tetratricopeptide repeat (TPR) [48453] (21 proteins)
   this is a repeat family; one repeat unit is 1zb1 A:166-231 found in domain

6. Protein Menin C-terminal domain [310725] (2 species)

7. Species Human (Homo sapiens) [TaxId:9606] [310974] (33 PDB entries)

8. Domain d5ddaa2: 5dda A:231-587 [310401]
   Other proteins in same PDB: d5ddaa1
   automated match to d3u85a2
   complexed with 59m, dms, edo, pge, so4

Details for d5ddaa2

PDB Entry: 5dda, 1.83 Å

PDB Description: menin in complex with mi-333

PDB Compounds: (A:) Menin

SCOPe Domain Sequences for d5ddaa2:

Sequence, based on SEQRES records:

>d5ddaa2 a.118.8.1 (A:231-587) Menin C-terminal domain {Human (Homo sapiens) [TaxId: 9606]}
drkmevafmvcainpsidlhtdslellqlqqkllwllydlghlerypmalgnladleele
ptpgrpdpltlyhkgiasaktyyrdehiypymylagyhcrnrnvrealqawadtatviqd
ynycredeeiykeffevandvipnllkeaaslleagsqgsalqdpecfahllrfydgick
weegsptpvlhvgwatflvqslgrfegqvrqkvrivsvpapaaspppegpvltfqsekmk
gmkellvatkinssaiklqltaqsqvqm

Sequence, based on observed residues (ATOM records):

>d5ddaa2 a.118.8.1 (A:231-587) Menin C-terminal domain {Human (Homo sapiens) [TaxId: 9606]}
drkmevafmvcainpsidlhtdslellqlqqkllwllydlghlerypmalgnladleele
ptpgrpdpltlyhkgiasaktyyrdehiypymylagyhcrnrnvrealqawadtatviqd
ynycredeeiykeffevandvipnllkeaaslleagsqgsalqdpecfahllrfydgick
weegsptpvlhvgwatflvqslgrfegqvrqkvrivspvltfqsekmkgmkellvatkin
ssaiklqltaqsqvqm

Timeline for d5ddaa2:

• d5ddaa2 first appeared in SCOPe 2.06
  
• d5ddaa2 appears in the current release, SCOPe 2.08