SCOPe 2.08: Domain d4xsca_: 4xsc A:

Lineage for d4xsca_ (4xsc A:)

1. Root: SCOPe 2.08

2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)

3. Fold d.117: Thymidylate synthase/dCMP hydroxymethylase [55830] (1 superfamily)
   contains large mixed beta-sheet

4. Superfamily d.117.1: Thymidylate synthase/dCMP hydroxymethylase [55831] (2 families)
   automatically mapped to Pfam PF00303

5. Family d.117.1.1: Thymidylate synthase/dCMP hydroxymethylase [55832] (4 proteins)

6. Protein automated matches [190469] (17 species)
   not a true protein

7. Species Varicella-zoster virus (strain oka vaccine) [TaxId:341980] [311478] (3 PDB entries)

8. Domain d4xsca_: 4xsc A: [310053]
   automated match to d4ez8a_
   complexed with 1pe, bvp

Details for d4xsca_

PDB Entry: 4xsc, 2.9 Å

PDB Description: complex structure of thymidylate synthase from varicella zoster virus with a phosphorylated bvdu

PDB Compounds: (A:) Thymidylate synthase

SCOPe Domain Sequences for d4xsca_:

Sequence, based on SEQRES records:

>d4xsca_ d.117.1.1 (A:) automated matches {Varicella-zoster virus (strain oka vaccine) [TaxId: 341980]}
tltgelqylkqvddilrygvrkrdrtgigtlslfgmqarynlrnefpllttkrvfwravv
eellwfirgstdskelaakdihiwdiygsskflnrngfhkrhtgdlgpiygfqwrhfgae
ykdcqsnylqqgidqlqtvidtiktnpesrrmiisswnpkdiplmvlppchtlcqfyvan
gelscqvyqrsgdmglgvpfniagyalltyivahvtglktgdlihtmgdahiylnhidal
kvqlarspkpfpclkiirnvtdindfkwddfqldgynphp

Sequence, based on observed residues (ATOM records):

>d4xsca_ d.117.1.1 (A:) automated matches {Varicella-zoster virus (strain oka vaccine) [TaxId: 341980]}
tltgelqylkqvddilrygvrkrdrtgigtlslfgmqarynlrnefpllttkrvfwravv
eellwfirgstdskelaakdihiwdtgdlgpiygfqwrhfgaeykdcqsnylqqgidqlq
tvidtiktnpesrrmiisswnpkdiplmvlppchtlcqfyvangelscqvyqrsgdmglg
vpfniagyalltyivahvtglktgdlihtmgdahiylnhidalkvqlarspkpfpclkii
rnvtdindfkwddfqldgynphp

Timeline for d4xsca_:

• d4xsca_ first appeared in SCOPe 2.06
  
• d4xsca_ appears in SCOPe 2.07