SCOPe 2.06: Domain d1qtn.1: 1qtn A:,B:

Lineage for d1qtn.1 (1qtn A:,B:)

1. Root: SCOPe 2.06

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.17: Caspase-like [52128] (1 superfamily)
   3 layers, a/b/a; core: mixed beta-sheet of 6 strands, order 213456, strand 6 is antiparallel to the rest

4. Superfamily c.17.1: Caspase-like [52129] (3 families)
   mature protein may be composed of two chains folded in a single domain

5. Family c.17.1.1: Caspase catalytic domain [52130] (8 proteins)

6. Protein Caspase-8 [52135] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [52136] (7 PDB entries)

8. Domain d1qtn.1: 1qtn A:,B: [30999]
   complexed with dtd

Details for d1qtn.1

PDB Entry: 1qtn, 1.2 Å

PDB Description: crystal structure of the complex of caspase-8 with the tetrapeptide inhibitor ace-ietd-aldehyde

PDB Compounds: (A:) caspase-8, (B:) caspase-8

SCOPe Domain Sequences for d1qtn.1:

Sequence; same for both SEQRES and ATOM records:

>g1qtn.1 c.17.1.1 (A:,B:) Caspase-8 {Human (Homo sapiens) [TaxId: 9606]}
dkvyqmkskprgycliinnhnfakarekvpklhsirdrngthldagaltttfeelhfeik
phddctveqiyeilkiyqlmdhsnmdcficcilshgdkgiiygtdgqeapiyeltsqftg
lkcpslagkpkvffiqacqgdnyqkgipvetdXtryipdeadfllgmatvnncvsyrnpa
egtwyiqslcqslrercprgddiltiltevnyevsnkddkknmgkqmpqptftlrkklvf
psd

Timeline for d1qtn.1:

• d1qtn.1 first appeared (with stable ids) in SCOP 1.55
  
• d1qtn.1 appears in SCOPe 2.05
  
• d1qtn.1 appears in SCOPe 2.07
  
• d1qtn.1 appears in the current release, SCOPe 2.08