Lineage for d4twya_ (4twy A:)

  1. Root: SCOPe 2.08
  2. 2739516Class b: All beta proteins [48724] (180 folds)
  3. 2794584Fold b.47: Trypsin-like serine proteases [50493] (1 superfamily)
    barrel, closed; n=6, S=8; greek-key
    duplication: consists of two domains of the same fold
  4. 2794585Superfamily b.47.1: Trypsin-like serine proteases [50494] (5 families) (S)
  5. 2797303Family b.47.1.4: Viral cysteine protease of trypsin fold [50603] (5 proteins)
  6. 2797364Protein Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) [74979] (8 species)
    contains an extra alpha-helical domain
  7. 2797397Species SARS coronavirus [TaxId:227859] [89349] (86 PDB entries)
  8. 2797428Domain d4twya_: 4twy A: [309675]
    automated match to d1z1ja_
    complexed with 3bl
    has additional subdomain(s) that are not in the common domain

Details for d4twya_

PDB Entry: 4twy (more details), 1.6 Å

PDB Description: structure of sars-3cl protease complex with a phenylbenzoyl (s,r)-n- decalin type inhibitor
PDB Compounds: (A:) 3C-like proteinase

SCOPe Domain Sequences for d4twya_:

Sequence; same for both SEQRES and ATOM records: (download)

>d4twya_ b.47.1.4 (A:) Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) {SARS coronavirus [TaxId: 227859]}
sgfrkmafpsgkvegcmvqvtcgtttlnglwlddtvycprhvictaedmlnpnyedllir
ksnhsflvqagnvqlrvighsmqncllrlkvdtsnpktpkykfvriqpgqtfsvlacyng
spsgvyqcamrpnhtikgsflngscgsvgfnidydcvsfcymhhmelptgvhagtdlegk
fygpfvdiqtaqaagtdttitlnvlawlyaavingdrwflnrftttlndfnlvamkynye
pltqdhvdilgplsaqtgiavldmcaalkellqngmngrtilgstiledeftpfdvvrqc
sgvtfq

SCOPe Domain Coordinates for d4twya_:

Click to download the PDB-style file with coordinates for d4twya_.
(The format of our PDB-style files is described here.)

Timeline for d4twya_: