Lineage for d4qvwl_ (4qvw L:)

  1. Root: SCOPe 2.07
  2. 2494617Class d: Alpha and beta proteins (a+b) [53931] (388 folds)
  3. 2548740Fold d.153: Ntn hydrolase-like [56234] (2 superfamilies)
    4 layers: alpha/beta/beta/alpha; has an unusual sheet-to-sheet packing
  4. 2548741Superfamily d.153.1: N-terminal nucleophile aminohydrolases (Ntn hydrolases) [56235] (8 families) (S)
    N-terminal residue provides two catalytic groups, nucleophile and proton donor
  5. 2548925Family d.153.1.4: Proteasome subunits [56251] (4 proteins)
  6. 2549037Protein Proteasome alpha subunit (non-catalytic) [56255] (9 species)
    contains an extension to the common fold at the N-terminus
  7. 2549053Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [56257] (235 PDB entries)
    The structure of yeast proteasome complexed with the proteasome activator pa26 is available from PDB (1fnt). The 1FNT entry designates protein chains by both upper case and lower case letters creating problems with its processing and presentation in SCOP; the proteasome activator pa26 structure is classified elsewhere in SCOP (a.24.8)
  8. 2549768Domain d4qvwl_: 4qvw L: [308579]
    Other proteins in same PDB: d4qvwb_, d4qvwc_, d4qvwf_, d4qvwg_, d4qvwh_, d4qvwm_, d4qvwp_, d4qvwq_, d4qvwt_, d4qvwu_, d4qvwv_
    automated match to d4j70l_
    complexed with bo2, cl, mg; mutant

Details for d4qvwl_

PDB Entry: 4qvw (more details), 3 Å

PDB Description: yCP beta5-A49S-mutant in complex with bortezomib
PDB Compounds: (L:) Proteasome subunit beta type-6

SCOPe Domain Sequences for d4qvwl_:

Sequence; same for both SEQRES and ATOM records: (download)

>d4qvwl_ d.153.1.4 (L:) Proteasome alpha subunit (non-catalytic) {Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932]}
qfnpygdnggtilgiagedfavlagdtrnitdysinsryepkvfdcgdnivmsangfaad
gdalvkrfknsvkwyhfdhndkklsinsaarniqhllygkrffpyyvhtiiagldedgkg
avysfdpvgsyereqcraggaaaslimpfldnqvnfknqyepgtngkvkkplkylsveev
iklvrdsftsaterhiqvgdgleilivtkdgvrkefyelkrd

SCOPe Domain Coordinates for d4qvwl_:

Click to download the PDB-style file with coordinates for d4qvwl_.
(The format of our PDB-style files is described here.)

Timeline for d4qvwl_: