SCOPe 2.08: Domain d4qvmc1: 4qvm C:1-234

Lineage for d4qvmc1 (4qvm C:1-234)

1. Root: SCOPe 2.08

2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)

3. Fold d.153: Ntn hydrolase-like [56234] (2 superfamilies)
   4 layers: alpha/beta/beta/alpha; has an unusual sheet-to-sheet packing

4. Superfamily d.153.1: N-terminal nucleophile aminohydrolases (Ntn hydrolases) [56235] (8 families)
   N-terminal residue provides two catalytic groups, nucleophile and proton donor

5. Family d.153.1.0: automated matches [191393] (1 protein)
   not a true family

6. Protein automated matches [190509] (19 species)
   not a true protein

7. Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:559292] [256123] (110 PDB entries)

8. Domain d4qvmc1: 4qvm C:1-234 [308451]
   Other proteins in same PDB: d4qvma_, d4qvmb_, d4qvmc2, d4qvmd_, d4qvme_, d4qvmf_, d4qvmg_, d4qvmh_, d4qvmi_, d4qvmj_, d4qvmk_, d4qvml_, d4qvmm_, d4qvmn_, d4qvmo_, d4qvmp_, d4qvmq2, d4qvmr_, d4qvms_, d4qvmt_, d4qvmu_, d4qvmv_, d4qvmw_, d4qvmx_, d4qvmy_, d4qvmz_
   automated match to d4eu2a_
   complexed with bo2, cl, mg; mutant

Details for d4qvmc1

PDB Entry: 4qvm, 2.8 Å

PDB Description: yCP beta5-M45A mutant in complex with bortezomib

PDB Compounds: (C:) Proteasome subunit alpha type-4

SCOPe Domain Sequences for d4qvmc1:

Sequence; same for both SEQRES and ATOM records:

>d4qvmc1 d.153.1.0 (C:1-234) automated matches {Baker's yeast (Saccharomyces cerevisiae) [TaxId: 559292]}
gydralsifspdghifqveyaleavkrgtcavgvkgkncvvlgcerrstlklqdtritps
kvskidshvvlsfsglnadsriliekarveaqshrltledpvtveyltryvagvqqrytq
sggvrpfgvstliagfdprddepklyqtepsgiysswsaqtigrnsktvrefleknydrk
eppatveecvkltvrsllevvqtgaknieitvvkpdsdivalsseeinqyvtqi

Timeline for d4qvmc1:

• d4qvmc1 first appeared in SCOPe 2.06, called d4qvmc_
  
• d4qvmc1 was called d4qvmc_ in SCOPe 2.07