SCOPe 2.06: Domain d4n56a2: 4n56 A:423-832

Lineage for d4n56a2 (4n56 A:423-832)

1. Root: SCOPe 2.06

2. Class e: Multi-domain proteins (alpha and beta) [56572] (69 folds)

3. Fold e.8: DNA/RNA polymerases [56671] (1 superfamily)
   divided into morphological domains including "palm", "thumb" and "fingers"; the catalytic "palm" domain is conserved to all members

4. Superfamily e.8.1: DNA/RNA polymerases [56672] (7 families)
   "palm" domain has a ferredoxin-like fold, related to that of an adenylyl cyclase domain

5. Family e.8.1.1: DNA polymerase I [56673] (5 proteins)

6. Protein DNA polymerase I (Klenow fragment) [56674] (3 species)

7. Species Thermus aquaticus [TaxId:271] [56676] (29 PDB entries)

8. Domain d4n56a2: 4n56 A:423-832 [307750]
   Other proteins in same PDB: d4n56a1
   automated match to d3rrha2
   protein/DNA complex; complexed with gol, mg, mn; mutant

Details for d4n56a2

PDB Entry: 4n56, 2.2 Å

PDB Description: Binary complex structure of Klenow fragment of Taq DNA polymerase I707L mutant (Cs3C KlenTaq) with DNA

PDB Compounds: (A:) DNA polymerase I, thermostable

SCOPe Domain Sequences for d4n56a2:

Sequence, based on SEQRES records:

>d4n56a2 e.8.1.1 (A:423-832) DNA polymerase I (Klenow fragment) {Thermus aquaticus [TaxId: 271]}
eerllwlyreverplsavlahmeatgvrldvaylralslevaeeiarleaevfrlaghpf
nlnsrdqlervlfdelglpaigktektgkrstsaavlealreahpivekilqyreltklk
styidplpdlihprtgrlhtrfnqtatatgrlsssdpnlqnipvrtplgqrirrafiaee
gwllvaldysqielrvlahlsgdenlirvfqegrdihtetaswmfgvpreavdplmrraa
ktinfgvlygmsahrlsqelaipyeeaqafieryfqsfpkvrawlektleegrrrgyvet
lfgrrryvpdlearvksvreaaermafnmpvqgtaadlmklamvklfprleemgarmllq
vhdelvleapkeraeavarlakevmegvyplavplevevgigedwlsake

Sequence, based on observed residues (ATOM records):

>d4n56a2 e.8.1.1 (A:423-832) DNA polymerase I (Klenow fragment) {Thermus aquaticus [TaxId: 271]}
eerllwlyreverplsavlahmeatgvrldvaylralslevaeeiarleaevfrlaghpf
nlnsrdqlervlfdelglpaigktektgkrstsaavlealreahpivekilqyreltklk
styidplpdlihprtgrlhtrfnqtatatgrlsssdpnlqnipvrtplgqrirrafiaee
gwllvaldysqielrvlahlsgdenlirvfqegrdihtetaaktinfgvlygfpkvrawl
ektleegrrrgyvetlfgrrryvpdlearvksvreaaermafnmpvqgtaadlmklamvk
lfprleemgarmllqvhdelvleapkeraeavarlakevmegvyplavplevevgigedw
lsake

Timeline for d4n56a2:

• d4n56a2 is new in SCOPe 2.06-stable
  
• d4n56a2 appears in SCOPe 2.07
  
• d4n56a2 appears in the current release, SCOPe 2.08