SCOPe 2.06: Domain d4cjyd_: 4cjy D:

Lineage for d4cjyd_ (4cjy D:)

1. Root: SCOPe 2.06

2. Class d: Alpha and beta proteins (a+b) [53931] (385 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.0: automated matches [191359] (1 protein)
   not a true family

6. Protein automated matches [190417] (25 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [187294] (882 PDB entries)

8. Domain d4cjyd_: 4cjy D: [307124]
   Other proteins in same PDB: d4cjya1, d4cjya2, d4cjyb1, d4cjyb2
   automated match to d4nsta_

Details for d4cjyd_

PDB Entry: 4cjy, 3.15 Å

PDB Description: Crystal structure of the human CDK12-cyclinK complex

PDB Compounds: (D:) cyclin-dependent kinase 12

SCOPe Domain Sequences for d4cjyd_:

Sequence, based on SEQRES records:

>d4cjyd_ d.144.1.0 (D:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
cvdkfdiigiigegtygqvykakdkdtgelvalkkvrldnekegfpitaireikilrqli
hrsvvnmkeivtdkqdaldfkkdkgafylvfeymdhdlmgllesglvhfsedhiksfmkq
lmegleychkknflhrdikcsnillnnsgqikladfglarlynseesrpytnkvitlwyr
ppelllgeerytpaidvwscgcilgelftkkpifqanlelaqlelisrlcgspcpavwpd
viklpyfntmkpkkqyrrrlreefsfipsaaldlldhmltldpskrctaeqtlqsdfl

Sequence, based on observed residues (ATOM records):

>d4cjyd_ d.144.1.0 (D:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
cvdkfdiigiigegtygqvykakdkdtgelvalkkvrlkegfpitaireikilrqlihrs
vvnmkeivtdafylvfeymdhdlmgllhfsedhiksfmkqlmegleychkknflhrdikc
snillnnsgqikladfglarlynpytnkvitlwyrppelllgeerytpaidvwscgcilg
elftkkpifqanlelaqlelisrlcgspcpavwpdviklpyfntmkpkkqyrrrlreefs
fipsaaldlldhmltldpskrctaeqtlqsdfl

Timeline for d4cjyd_:

• d4cjyd_ is new in SCOPe 2.06-stable
  
• d4cjyd_ appears in SCOPe 2.07
  
• d4cjyd_ appears in the current release, SCOPe 2.08