Lineage for d3luhc_ (3luh C:)

  1. Root: SCOPe 2.07
  2. 2434694Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2482762Fold c.44: Phosphotyrosine protein phosphatases I-like [52787] (3 superfamilies)
    3 layers: a/b/a; parallel beta-sheet of 4 strands, order 2134
  4. 2482963Superfamily c.44.3: PIWI domain N-terminal-like [310581] (2 families) (S)
  5. 2482964Family c.44.3.1: PIWI domain N-terminal [310609] (4 proteins)
    PubMed 15565169 notes that both halves of PIWI are usually a single evolutionary unit; however, fragments have been characterized separately. The C-terminal half is (c.55.3.10)
  6. 2482978Protein Argonaute-2 [310718] (1 species)
    Pfam PF16487
  7. 2482979Species Human (Homo sapiens) [TaxId:9606] [310964] (12 PDB entries)
  8. 2482994Domain d3luhc_: 3luh C: [305881]
    automated match to d3luha_
    protein/RNA complex; complexed with 5gp, po4

Details for d3luhc_

PDB Entry: 3luh (more details), 2 Å

PDB Description: crystal structure of mid domain from hago2 in complex with gmp
PDB Compounds: (C:) Protein argonaute-2

SCOPe Domain Sequences for d3luhc_:

Sequence; same for both SEQRES and ATOM records: (download)

>d3luhc_ c.44.3.1 (C:) Argonaute-2 {Human (Homo sapiens) [TaxId: 9606]}
kqfhtgieikvwaiacfapqrqctevhlksfteqlrkisrdagmpiqgqpcfckyaqgad
svepmfrhlkntyaglqlvvvilpgktpvyaevkrvgdtvlgmatqcvqmknvqrttpqt
lsnlclkinvklg

SCOPe Domain Coordinates for d3luhc_:

Click to download the PDB-style file with coordinates for d3luhc_.
(The format of our PDB-style files is described here.)

Timeline for d3luhc_: