Lineage for d2cdda_ (2cdd A:)

  1. Root: SCOPe 2.07
  2. 2494617Class d: Alpha and beta proteins (a+b) [53931] (388 folds)
  3. 2537076Fold d.122: ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase [55873] (1 superfamily)
    8-stranded mixed beta-sheet; 2 layers: alpha/beta
  4. 2537077Superfamily d.122.1: ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase [55874] (5 families) (S)
  5. 2537078Family d.122.1.1: Heat shock protein 90, HSP90, N-terminal domain [55875] (2 proteins)
  6. 2537079Protein HSP90 [55876] (3 species)
  7. 2537164Species Human (Homo sapiens) [TaxId:9606] [55878] (144 PDB entries)
    Uniprot P08238 10-220 # HSP 90-beta isoform ! Uniprot P07900 16-223
  8. 2537213Domain d2cdda_: 2cdd A: [303656]
    automated match to d1uy7a_
    complexed with ct5

Details for d2cdda_

PDB Entry: 2cdd (more details), 1.9 Å

PDB Description: human hsp90 with 4-(4-(2,3-dihydro-benzol(1,4)dioxin-6-yl)-5-methyl- 1h-pyrazol-3-yl)-6-ethyl-benzene-1,3-diol
PDB Compounds: (A:) heat shock protein hsp-90 alpha

SCOPe Domain Sequences for d2cdda_:

Sequence; same for both SEQRES and ATOM records: (download)

>d2cdda_ d.122.1.1 (A:) HSP90 {Human (Homo sapiens) [TaxId: 9606]}
evetfafqaeiaqlmsliintfysnkeiflrelisnssdaldkiryesltdpskldsgke
lhinlipnkqdrtltivdtgigmtkadlinnlgtiaksgtkafmealqagadismigqfg
vgfysaylvaekvtvitkhnddeqyawessaggsftvrtdtgepmgrgtkvilhlkedqt
eyleerrikeivkkhsqfigypitlfvek

SCOPe Domain Coordinates for d2cdda_:

Click to download the PDB-style file with coordinates for d2cdda_.
(The format of our PDB-style files is described here.)

Timeline for d2cdda_: