Lineage for d5aava2 (5aav A:303-306)

  1. Root: SCOPe 2.06
  2. 2274070Class l: Artifacts [310555] (1 fold)
  3. 2274071Fold l.1: Tags [310573] (1 superfamily)
  4. 2274072Superfamily l.1.1: Tags [310607] (1 family) (S)
  5. 2274073Family l.1.1.1: Tags [310682] (2 proteins)
  6. 2280947Protein N-terminal Tags [310894] (1 species)
  7. 2280948Species Synthetic [311501] (10810 PDB entries)
  8. 2291273Domain d5aava2: 5aav A:303-306 [301774]
    Other proteins in same PDB: d5aava1, d5aavb_
    complexed with gw5

Details for d5aava2

PDB Entry: 5aav (more details), 1.95 Å

PDB Description: optimization of a novel binding motif to to (e)-3-(3,5- difluoro-4-((1r,3r)-2-(2-fluoro-2-methylpropyl)-3-methyl-2, 3,4,9-tetrahydro-1h-pyrido(3,4-b)indol-1-yl)phenyl)acrylic acid (azd9496), a potent and orally bioavailable selective estrogen receptor downregulator and antagonist
PDB Compounds: (A:) Estrogen receptor

SCOPe Domain Sequences for d5aava2:

Sequence; same for both SEQRES and ATOM records: (download)

>d5aava2 l.1.1.1 (A:303-306) N-terminal Tags {Synthetic}
gshm

SCOPe Domain Coordinates for d5aava2:

Click to download the PDB-style file with coordinates for d5aava2.
(The format of our PDB-style files is described here.)

Timeline for d5aava2:

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Domains from same chain:
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d5aava1
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Domains from other chains:
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d5aavb_