SCOPe 2.08: Domain d2ohxb2: 2ohx B:164-339

Lineage for d2ohxb2 (2ohx B:164-339)

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.2: NAD(P)-binding Rossmann-fold domains [51734] (1 superfamily)
   core: 3 layers, a/b/a; parallel beta-sheet of 6 strands, order 321456
   The nucleotide-binding modes of this and the next two folds/superfamilies are similar

4. Superfamily c.2.1: NAD(P)-binding Rossmann-fold domains [51735] (13 families)

5. Family c.2.1.1: Alcohol dehydrogenase-like, C-terminal domain [51736] (19 proteins)
   N-terminal all-beta domain defines family

6. Protein Alcohol dehydrogenase [51737] (9 species)

7. Species Horse (Equus caballus) [TaxId:9796] [51738] (53 PDB entries)
   Uniprot P00327

8. Domain d2ohxb2: 2ohx B:164-339 [29686]
   Other proteins in same PDB: d2ohxa1, d2ohxb1
   complexed with dms, nad, zn

Details for d2ohxb2

PDB Entry: 2ohx, 1.8 Å

PDB Description: refined crystal structure of liver alcohol dehydrogenase-nadh complex at 1.8 angstroms resolution

PDB Compounds: (B:) alcohol dehydrogenase

SCOPe Domain Sequences for d2ohxb2:

Sequence; same for both SEQRES and ATOM records:

>d2ohxb2 c.2.1.1 (B:164-339) Alcohol dehydrogenase {Horse (Equus caballus) [TaxId: 9796]}
splekvcligcgfstgygsavkvakvtqgstcavfglggvglsvimgckaagaariigvd
inkdkfakakevgatecvnpqdykkpiqevltemsnggvdfsfevigrldtmvtalsccq
eaygvsvivgvppdsqnlsmnpmlllsgrtwkgaifggfkskdsvpklvadfmakk

Timeline for d2ohxb2:

• d2ohxb2 first appeared (with stable ids) in SCOP 1.55
  
• d2ohxb2 appears in SCOPe 2.07